ID A0A3N0C332_9MICC Unreviewed; 490 AA.
AC A0A3N0C332;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Cardiolipin synthase {ECO:0000313|EMBL:RNL56409.1};
GN Name=cls {ECO:0000313|EMBL:RNL56409.1};
GN ORFNames=D7003_08725 {ECO:0000313|EMBL:RNL56409.1};
OS Arthrobacter oryzae.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=409290 {ECO:0000313|EMBL:RNL56409.1, ECO:0000313|Proteomes:UP000273807};
RN [1] {ECO:0000313|EMBL:RNL56409.1, ECO:0000313|Proteomes:UP000273807}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TNB02 {ECO:0000313|EMBL:RNL56409.1,
RC ECO:0000313|Proteomes:UP000273807};
RA Cho Y.-J., Cho A., Kim O.-S.;
RT "Genome sequencing of Arthrobacter oryzae TNB02.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNL56409.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; RBED01000086; RNL56409.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N0C332; -.
DR OrthoDB; 9762009at2; -.
DR Proteomes; UP000273807; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR CDD; cd09158; PLDc_EcCLS_like_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR022924; Cardiolipin_synthase.
DR InterPro; IPR027379; CLS_N.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR Pfam; PF13396; PLDc_N; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000273807};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 223..250
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 403..430
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 490 AA; 55258 MW; A5F1117556A94A93 CRC64;
MWPIPLAGTL PPWLIVVLTL IDLAIRVLAL GIIPGNRRPT TAMAWLLVIF FVPSVGLTLF
LLFGNFRLSR RRRAQQQAIN TRVRAGTSEL ASMESDYSGP EWVASAAELN KTLGSLPMVD
GNSVELLPGY PDSIKAMAAA VREAKTFVNA EFYIMSADHV TDDLLTALEE AAERGVEVRL
LFDHLGTLRI QGYRKLIRRL KASKIRWRPM LPLSPVHGQW RRPDLRNHRK IMVIDGEMAF
TGSQNLIEPS YNNSKHRKLG REWVELMACL RGPIVTTLNV VFATDWLSET DESLEEQLRH
RPEPSPGHVT AQAVPSGPGF ITENNLRLFN TLIYSAQHRI SICSPYFVPD DSLLYAVTTA
AQRGVDVELF VSEKGDQFLV HHAQQSFYKA LLEAGVRIYL YRAPFVLHAK HFTIDDEVAV
LGSSNMDMRS FSLNLEVSVM LLGSDIVQRV RAVEDTYRDI SKELLLEDWL KRPMRAKYVD
NVARLTATLQ
//
