ID   A0A3N0CGI8_9ACTN        Unreviewed;       319 AA.
AC   A0A3N0CGI8;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Acyl-CoA desaturase {ECO:0000313|EMBL:RNL62574.1};
GN   ORFNames=EFK50_12470 {ECO:0000313|EMBL:RNL62574.1};
OS   Nocardioides marmoriginsengisoli.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=661483 {ECO:0000313|EMBL:RNL62574.1, ECO:0000313|Proteomes:UP000267128};
RN   [1] {ECO:0000313|EMBL:RNL62574.1, ECO:0000313|Proteomes:UP000267128}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Gsoil 097 {ECO:0000313|EMBL:RNL62574.1,
RC   ECO:0000313|Proteomes:UP000267128};
RA   Li F.;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RNL62574.1}.
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DR   EMBL; RJSE01000007; RNL62574.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N0CGI8; -.
DR   OrthoDB; 19906at2; -.
DR   Proteomes; UP000267128; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd03505; Delta9-FADS-like; 1.
DR   InterPro; IPR015876; Acyl-CoA_DS.
DR   InterPro; IPR005804; FA_desaturase_dom.
DR   PANTHER; PTHR11351; ACYL-COA DESATURASE; 1.
DR   PANTHER; PTHR11351:SF3; STEAROYL-COA 9-DESATURASE; 1.
DR   Pfam; PF00487; FA_desaturase; 1.
DR   PRINTS; PR00075; FACDDSATRASE.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000267128};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        28..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        58..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        180..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          52..273
FT                   /note="Fatty acid desaturase"
FT                   /evidence="ECO:0000259|Pfam:PF00487"
SQ   SEQUENCE   319 AA;  36083 MW;  DB86D57FA20BB2CD CRC64;
     MTASPVLDEP ITQHATMGGD TQSLTEQVAL GIFIAVPFLA LLAAIPIAWG GWLGWSDLLI
     MGAMYWFTGH GITVGFHRLF THKSFKPNRF VKNALAVAGS MAVQGPLVRW VADHRKHHKF
     SDRDGDPHSP WKYGTNLRAL WKGFWHAHMM WLFDSEQTVQ RKYAPDLLKD RDLIRISRHF
     WAFVLLSMLL PAALGGLITW SWQGALTAFF WGSLVRVALL HHVTWSINSI CHTIGDRPFV
     SRDKSANVWW LAIPSMGESW HNLHHADPTC ARHGVQRGQL DTSARLIWLL EKAGWVKEVR
     WPVAERIQAK LVSAQPVSS
//