ID   A0A3N0CS59_9ACTN        Unreviewed;       308 AA.
AC   A0A3N0CS59;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=TetR/AcrR family transcriptional regulator {ECO:0000313|EMBL:RNL66298.1};
GN   ORFNames=EFK50_00915 {ECO:0000313|EMBL:RNL66298.1};
OS   Nocardioides marmoriginsengisoli.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=661483 {ECO:0000313|EMBL:RNL66298.1, ECO:0000313|Proteomes:UP000267128};
RN   [1] {ECO:0000313|EMBL:RNL66298.1, ECO:0000313|Proteomes:UP000267128}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Gsoil 097 {ECO:0000313|EMBL:RNL66298.1,
RC   ECO:0000313|Proteomes:UP000267128};
RA   Li F.;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RNL66298.1}.
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DR   EMBL; RJSE01000001; RNL66298.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N0CS59; -.
DR   OrthoDB; 70491at2; -.
DR   Proteomes; UP000267128; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR   Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR   PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR   PANTHER; PTHR30055:SF160; TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)-RELATED; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   PRINTS; PR00455; HTHTETR.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW   Reference proteome {ECO:0000313|Proteomes:UP000267128};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          112..172
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50977"
FT   DNA_BIND        135..154
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT   REGION          29..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..77
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..102
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   308 AA;  33576 MW;  354D2F836848AB07 CRC64;
     MVSSAAGSTS AGRDTTLLGA NLLELGTPVQ HRRSLQCSPP RRAADPRVRH LEPPEPPSTR
     QYVRVGSPQT GLDASQDRPP LTRTARRLRV TTPATRSTSG DQPARGARLP RRARRAQLLE
     SALEVFVAQG YHSAAMDDIA ESAGVSKPVL YQHFPGKLDL YLALLDQAVE KVIAGTREAL
     ESTEDNKQRV AATMTAFYTY VASEQGEFRL VFESDLTNEP AVRERIDRVT LECAELIAHV
     IHDDTGLPDE ASRLLAVALV GMGQVSARFW LESRLQGNDT MEQADAASLV AGLAWRGIRG
     YPRTDEPG
//