ID   A0A3N0DQ69_9ACTN        Unreviewed;       361 AA.
AC   A0A3N0DQ69;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN   ORFNames=EFL95_16725 {ECO:0000313|EMBL:RNL77651.1};
OS   Nocardioides marmorisolisilvae.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=1542737 {ECO:0000313|EMBL:RNL77651.1, ECO:0000313|Proteomes:UP000277094};
RN   [1] {ECO:0000313|EMBL:RNL77651.1, ECO:0000313|Proteomes:UP000277094}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIS18-7 {ECO:0000313|EMBL:RNL77651.1,
RC   ECO:0000313|Proteomes:UP000277094};
RA   Li F.;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RNL77651.1}.
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DR   EMBL; RJSG01000003; RNL77651.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N0DQ69; -.
DR   OrthoDB; 4080114at2; -.
DR   Proteomes; UP000277094; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   PANTHER; PTHR14226:SF29; NEUROPATHY TARGET ESTERASE SWS; 1.
DR   PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277094}.
FT   DOMAIN          77..252
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..32
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   361 AA;  38718 MW;  50B395998451C25E CRC64;
     MSTPPLGPWM QHLGGHSSHE TYRPTTDTSV GNSIKRLNSD IGKPMNSVIT TEDPSSTTAQ
     GGAMNEQKVT KNTRDVFVLS GGASRGAVQV GMMQTLIEAG IVPDGLVGSS VGALNAAFMG
     WQPGPERVSK LADQWLRLQT RDIFPGGNWT RLSHLARRHS YLFDSYALSS LIHAWVPVRN
     LEELTVPVRI TTTPLASCAA KYHDRGPIEK ILLASAAVPG VFEPVELVDE DGARSTHVDG
     GVADLIPVAG TVALAPTRVF VLDATVPVRI PRARTPIEIL IASLGIAVRV RPMPDLGPDV
     EVHHLTAPDL GTGMIDFSRS AEHIALGRKV AAELVESLGV KPAPLTDRPH RFWDRFSKSA
     A
//