ID A0A3N0DQT4_9ACTN Unreviewed; 969 AA.
AC A0A3N0DQT4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Acyltransferase domain-containing protein {ECO:0000313|EMBL:RNL77992.1};
DE Flags: Fragment;
GN ORFNames=EFW17_23580 {ECO:0000313|EMBL:RNL77992.1};
OS Nocardiopsaceae bacterium YIM 96095.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae.
OX NCBI_TaxID=2487137 {ECO:0000313|EMBL:RNL77992.1, ECO:0000313|Proteomes:UP000269198};
RN [1] {ECO:0000313|EMBL:RNL77992.1, ECO:0000313|Proteomes:UP000269198}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 96095 {ECO:0000313|EMBL:RNL77992.1,
RC ECO:0000313|Proteomes:UP000269198};
RA Tang S.-K., Chunyu W.-X., Feng Y.-Z.;
RT "The genome draft of YIM 96095.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNL77992.1}.
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DR EMBL; RJMB01000051; RNL77992.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N0DQT4; -.
DR OrthoDB; 4537517at2; -.
DR Proteomes; UP000269198; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF51; PHENOLPHTHIOCEROL_PHTHIOCEROL POLYKETIDE SYNTHASE SUBUNIT E; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:RNL77992.1};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000269198};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:RNL77992.1}.
FT DOMAIN 1..347
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 845..920
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 923..945
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RNL77992.1"
FT NON_TER 969
FT /evidence="ECO:0000313|EMBL:RNL77992.1"
SQ SEQUENCE 969 AA; 102814 MW; 447087AF6446F28F CRC64;
SPREALAIDP QQRVLLETCW EALEHSRVDP ASLRGSRTGV YMGAMAQEYG PPMGEAADGL
EGFLLTGGAE SVISGRVAYT LGLEGPAVTM DTACSSSLVS LHLACQALQR QECSLALAGG
VTVMADPGIF VEFSRQRGIA PDGRCKTFSA AADGTGWAEG AGVLVLERLS DARRNGHRIL
AVIRGSAVNQ DGASNGITAP NGPSQERVIR QALEAAGLEP ADVDAVEAHG TGTTLGDPIE
AQALISTYGQ DRPDERPLRI GSIKSNVGHT QAAAGVAGVI KMVEALRHRT LPRSLHIDEP
SPHVDWSEGG VRPLAAAEPW PDTGRPARAG VSSFGVSGTN AHVVVEEPPH QPTETEPDHA
EQPPTDTPLP WVVSAKSAAA LRAQAGRLRS AVTADPALGP VEVGYSLAVT RTAMDHRAVV
LADHRDGHLR GLDALARGDE SAEVVRGDAV NAGQPVLVFP GQGSQWVGMA ADLLQRSEVF
GDSMNECARA LEPYVDWSLL DVVRSTNGAP GLDRIDVVQP ALFAVNVSLA RLWRSYGVEP
AAVVGHSQGE VAAAHVAGAL SLEDATRIIA LRSQLLLALR GKGSLVSLGV GADDAEALLE
PWRDTMSVAG HNGPTSTVVS GTPDAVADLV AACEARGVRA REIPASVPTH SHHADEVRDE
LFEMLSGISP RSGEIPFYST VRGERVDHAE LATQYWFDNM RYPVLFDPTV REIAERGHHT
FVETSPHPVL TVGTQEILES AGVTDPVVLG TLRRDEDGPR RFLTSLAEAH VRGVDVQWQR
AFDDHAPTIV DLPTYPFQRS RYWLATRRSS GGSDALGQVV APAEPEETSE LVRRLSGMTT
RERHDALLDL VSTHAAQVLG HSSAEAIMAT RPFIEMGFDS LTSVELRNRL GKATGLRLPT
TLLFDHPSPE AVASELGRRL TPGTTTVTAT AGTDRRHKGS DPWVGDRLSE PVAIVGMGCR
YPGGVSSPE
//
