ID A0A3N0E5P7_9ACTN Unreviewed; 465 AA.
AC A0A3N0E5P7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Tyrosine phenol-lyase {ECO:0000313|EMBL:RNL83162.1};
DE EC=4.1.99.2 {ECO:0000313|EMBL:RNL83162.1};
GN ORFNames=EFW17_16800 {ECO:0000313|EMBL:RNL83162.1};
OS Nocardiopsaceae bacterium YIM 96095.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae.
OX NCBI_TaxID=2487137 {ECO:0000313|EMBL:RNL83162.1, ECO:0000313|Proteomes:UP000269198};
RN [1] {ECO:0000313|EMBL:RNL83162.1, ECO:0000313|Proteomes:UP000269198}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 96095 {ECO:0000313|EMBL:RNL83162.1,
RC ECO:0000313|Proteomes:UP000269198};
RA Tang S.-K., Chunyu W.-X., Feng Y.-Z.;
RT "The genome draft of YIM 96095.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR611166-50};
CC -!- SIMILARITY: Belongs to the beta-eliminating lyase family.
CC {ECO:0000256|ARBA:ARBA00009721}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNL83162.1}.
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DR EMBL; RJMB01000018; RNL83162.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N0E5P7; -.
DR OrthoDB; 9764079at2; -.
DR Proteomes; UP000269198; Unassembled WGS sequence.
DR GO; GO:0050371; F:tyrosine phenol-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0009072; P:aromatic amino acid metabolic process; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR011166; Beta-eliminating_lyase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR32325; BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32325:SF4; TRYPTOPHANASE; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF001386; Trpase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:RNL83162.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR611166-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000269198}.
FT DOMAIN 48..424
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 259
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR611166-50"
SQ SEQUENCE 465 AA; 51187 MW; 8F426B1A55CAB42E CRC64;
MSPRHPAEPW RIKMVEPLPT TSRPHRRQAL EKAGYNISLL RSEDVYIDLY TDSGTNAMSD
HQWAAMMIGD ESYAGARSFY RLEAAVHEYY GYEHVIPTHQ GRGAENILSR MLIRPGHHIP
GNMYFTTTRA HQELNGGTFH DVIIDEAHDP ACEHPFKGDV DLAKLERLIH DLGPDRIPYV
CVAATVNMAG GQPISLANLA EVHELARRHG ILVILDAARA VENAWFIKQR EPGWGEHSVA
AILREICART DGAAMSAKKD SLANIGGWLA VRDPDLAESA RELVVLYEGL HTYGGMTGRD
MEAIAVGIAE SVREENVSAR IDQVAYLGRR LAEAGLPLVR PVGGHAVCID AGAALPQVPR
DQFPAQTLAA ALYLDSGVRA AERGVVSAGR DPATGHNRHP QLELIRLTVP RRVYTQSHMD
LVADSAVRVH EQHAHLHSGL VFLHEPETLR FFQARFAPAT SDSPI
//
