ID   A0A3N1ANL4_9ACTN        Unreviewed;      1209 AA.
AC   A0A3N1ANL4;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=AAA domain-containing protein {ECO:0000313|EMBL:ROO58389.1};
GN   ORFNames=EDC02_0144 {ECO:0000313|EMBL:ROO58389.1};
OS   Micromonospora sp. Llam0.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=2485143 {ECO:0000313|EMBL:ROO58389.1, ECO:0000313|Proteomes:UP000275308};
RN   [1] {ECO:0000313|EMBL:ROO58389.1, ECO:0000313|Proteomes:UP000275308}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Llam0 {ECO:0000313|EMBL:ROO58389.1,
RC   ECO:0000313|Proteomes:UP000275308};
RA   D'Agostino P.;
RT   "Genome mining of underrepresented organisms for secondary metabolites.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ROO58389.1}.
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DR   EMBL; RJJY01000001; ROO58389.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N1ANL4; -.
DR   OrthoDB; 4464809at2; -.
DR   Proteomes; UP000275308; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR029030; Caspase-like_dom_sf.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011600; Pept_C14_caspase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR43788:SF8; HELICASE WITH ZINC FINGER 2; 1.
DR   Pfam; PF13086; AAA_11; 2.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF00656; Peptidase_C14; 1.
DR   SUPFAM; SSF52129; Caspase-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000275308}.
FT   DOMAIN          3..216
FT                   /note="Peptidase C14 caspase"
FT                   /evidence="ECO:0000259|Pfam:PF00656"
FT   DOMAIN          509..586
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          826..866
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          908..1079
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
FT   REGION          646..673
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1209 AA;  131194 MW;  98071F2098882A8B CRC64;
     MGRHALLLGT ASYHADRQLP PLPSVRQDVT QLKTLLDGSG GFDTVDARLD LPVAHLRQVV
     EDFYGRCGRD DLALLYYSGH GVLHEDRESL FLAATDSHAG QLHATAFDVD GTLRHLLNST
     KASQKVVLLD CCFSGAFTAR HRFRGGVREE PRRGKRERGT FILTSSTHMK ASKAQGADRP
     SVFTEVLLDG LRGAADGSAD GWVTTNDLSR YAMTEMARRR QHSPVESSEG VTEPIRLVAA
     PDSTAARAQA DAGPATPADD APFDADQWRR LITYYVNCME RSAVLRSFID PQAVSTYTPA
     PAGAEAVFTA TSPVRLTGRA SALAARARAD GKELQYGYPV VAVRPTRQQP VRLTPLLICD
     VTVGTNDVVH AAFPPRPGPA LLDLLQLSDV ESDELLQRVG QVFAPGDPAA LTATVDLLTK
     TFGLTPVADL DPMALVGAPR PGPLDRVQNA ALLYSVDASA SPQQQLVADL QSMIKNPRLI
     DRTALATLAA GPGEEAPVSI TTVALAPANE AQEEIIRAAM SQPLTVAQGP PGTGKSQLVT
     ALLATATAAG QSVLIGSTSN QAVDAVIGRV GELVGPGLVL RTGNKEHRLQ EPKHIADLIA
     AYPPAESHLA PDDRTPLYEL RLISDEISSL RQSLDDQRLL ERDLADLAAE RRPGPRHEHR
     TGHEHRADRD AAAVGLPDDD DALAQLYRLT DRALTSRWLG WWYRWRLRRH GAGDPGTIRA
     LGERTVIELR WRDCRRQADA LPDADTSWQR LTELIGVERP RRSIELLRAQ IARRVTSGAR
     LLQNRADEMA RAQSDSWAYF PELLRVLPGW AVTALSVRRL RREPAMYDLV VIDEAAQCTV
     PAILPMLYRA KRALIIGDPR QLPPVVELSD TDDRTEQAKA GLGAGWLDTR RLRYARHSAY
     DAFAAAAGTA YLLDEHYRCH PDIVDAPNRE VYQGRLTVLT DPARLTAPAE PAVRWRDVPG
     TFSYGPTGSG RNDVEIAAVV TEVAELRAAY PEASIGVVTP LAAQQRGLKS ALQAAGLTEN
     LLCATIHRFQ GSERDIMVVS PVGAHGIGDR TRDWLAHQTN LWNVAITRAR SQLVVVGDRS
     WWSGQRGLLT AVALGRTSTA ELPDAAPGPA DQLHRALGEA GVAVRRDVAL AGQTADLVIR
     QAGREIAVYV DDPAGDPSGR ALRKVLARLD VAAHHGTVRR VPAWRCLAEP EQVATELSEQ
     LRQLNLAGR
//