ID A0A3N1AP16_9ACTN Unreviewed; 727 AA.
AC A0A3N1AP16;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Diguanylate cyclase (GGDEF)-like protein {ECO:0000313|EMBL:ROO58537.1};
GN ORFNames=EDC02_0299 {ECO:0000313|EMBL:ROO58537.1};
OS Micromonospora sp. Llam0.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=2485143 {ECO:0000313|EMBL:ROO58537.1, ECO:0000313|Proteomes:UP000275308};
RN [1] {ECO:0000313|EMBL:ROO58537.1, ECO:0000313|Proteomes:UP000275308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Llam0 {ECO:0000313|EMBL:ROO58537.1,
RC ECO:0000313|Proteomes:UP000275308};
RA D'Agostino P.;
RT "Genome mining of underrepresented organisms for secondary metabolites.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROO58537.1}.
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DR EMBL; RJJY01000001; ROO58537.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N1AP16; -.
DR OrthoDB; 23692at2; -.
DR Proteomes; UP000275308; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000275308};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 18..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 281..414
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 436..690
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT REGION 694..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 727 AA; 77443 MW; 078ED7CE47732915 CRC64;
MEAAALRNSV PSERAPGFFG FVGGVTAAAL AVCAVPLLNL PAQISDLPAA FWLMALLAVV
GDARPFTPPG RRRRSEVFPS VCFTFAILLA WGLGPAVAVQ AVAVAVFAWR ARHVPWRALF
NSSQYALALA AAAAVAGLAG PGVFAGTAEL AWSDVAVAVG AAAAWSAVNY STVTLAIRLR
FGGRWWRSAR RGIGFELSST GSLLLLGPVL VVAGQVDPAL IPLVLVPLYA VYRMAALASE
QERSARLDPL TGLANRKALI VEIADQVPAH ADALRRGAPD SRMALLLLDL DRFKRVNDAL
GHLVGDRLLV EVGLRLAMVV RPQDLVVRLG GDEFAILATR LTGADEAREI AEQVVTALAE
PVALDGLPLD VGGSVGIALY PEHGGDFATL LQHADVAMYD AKDTGDGTAV YAAESDHNTP
ERLSLLADLR RVLDVNGAHA ADPGREVDDV GEITMYYQPQ VEIATGEVVG VEALLRWRHP
RRGMVDPEEL IKVAEQSAVM RLLTRRVVDD VVEQIAKWAA AGVTLRAAVN VSVRDLHTGE
IADQISDRLT RYNLSPDQLQ LEITEGALMA DPRRVLATIS RLDAIGVAIA LDDFGTGYSS
MQHLRRLPLS EVKIDRSFVL GMAADTDDAA IVRSVIELAR ALGLRVVAEG VEDDASWRRL
SALGCHVAQG WFYARPMPAD ELVSWLARYR PLVPGPRGVP PGPSDDSPDA PADPPGPPDD
SAGPPEK
//
