ID   A0A3N1CWR6_9ACTN        Unreviewed;       845 AA.
AC   A0A3N1CWR6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Peptidase M48-like protein {ECO:0000313|EMBL:ROO85740.1};
GN   ORFNames=EDD29_3289 {ECO:0000313|EMBL:ROO85740.1};
OS   Actinocorallia herbida.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinocorallia.
OX   NCBI_TaxID=58109 {ECO:0000313|EMBL:ROO85740.1, ECO:0000313|Proteomes:UP000272400};
RN   [1] {ECO:0000313|EMBL:ROO85740.1, ECO:0000313|Proteomes:UP000272400}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44254 {ECO:0000313|EMBL:ROO85740.1,
RC   ECO:0000313|Proteomes:UP000272400};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ROO85740.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; RJKE01000001; ROO85740.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N1CWR6; -.
DR   Proteomes; UP000272400; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR001915; Peptidase_M48.
DR   Pfam; PF01435; Peptidase_M48; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000272400};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   TRANSMEM        12..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        80..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        206..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        231..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        345..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        380..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        416..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        451..474
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        494..516
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        537..555
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        588..610
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        622..646
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        666..691
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        712..735
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          162..261
FT                   /note="Peptidase M48"
FT                   /evidence="ECO:0000259|Pfam:PF01435"
SQ   SEQUENCE   845 AA;  88406 MW;  080CD938E5FA3C2E CRC64;
     MTPGPGPNTT SRFALLAVTA TVTAYFLHGL TLTALSAAFD LPWGDLSGGC VDGVRHEGVP
     PGEFAADFRV CLYRAGVLNV LVRLGLVVVT FGVAAALYLR HSRARWPLTS LDAVAATDGQ
     AVEHVRDVLA EHGDVEATVL FRLNQTGAEG RTYGLPGSYR VELSDALLEG EPGSPERDLK
     RLRGVLRHEL AHLRNRDVGV TQLTIALRRS VLGTAALPAL LAWTTRPQSP AILLAVALSA
     ALLWLEYAAV LRAREYHADA AVQDPDFVQV LRDMEKARPK TPIQVLFDFH PPWRERAKRR
     ESPGLLLRPA AFDGFAAGML VGFSYLPFAQ ATGVIGPRDT ALTAWLAGLP FAVLLSGIAG
     VSLARAMWGA RFQGMAEPRS HTMAAALACG VLAGQSFPLT DTPLTAWSDV LRHHPVVGLC
     WAVVLFLLLW AFCSWQVLLT EAWIGAGLVR WSAGTAYLIL SGGAVLGVWI GFWFHGLQQL
     RALDDPWEGL GVNGLLLIID TRFVLVVLAA ALLPLAPPAV VRLLGRRPAF GPVAAPRAWT
     IGVAAVLGIG VHLVAGNPLH RDLREEMTAL APQVGSGAVG DGAAVLPLLP VAILAAAVTA
     AVAVAAAFSA RGHWLARHRF PAAVLGAMAG AAVAGPLMFV HLLASFCGWS GAYTCLRAAD
     PPLKSLAGLS LWTLAFALPA ALAVVALLQA VTARARPRRR PPSRPSGRVG AAAKAVPAAL
     AWTLAAISVA AAALATGAEQ AGPPSRTPPV GLEEVLAGIR PGATSLARAC RDVEAEINSG
     GVHTTVTGSL GLVYAGYTVR YASTDDPVAS ALARASVAAL REGDVPESGA VILSMQRYCA
     IATAG
//