ID   A0A3N1DCS2_9ACTN        Unreviewed;       694 AA.
AC   A0A3N1DCS2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:ROO90928.1};
GN   ORFNames=EDD29_8670 {ECO:0000313|EMBL:ROO90928.1};
OS   Actinocorallia herbida.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinocorallia.
OX   NCBI_TaxID=58109 {ECO:0000313|EMBL:ROO90928.1, ECO:0000313|Proteomes:UP000272400};
RN   [1] {ECO:0000313|EMBL:ROO90928.1, ECO:0000313|Proteomes:UP000272400}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44254 {ECO:0000313|EMBL:ROO90928.1,
RC   ECO:0000313|Proteomes:UP000272400};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ROO90928.1}.
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DR   EMBL; RJKE01000001; ROO90928.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N1DCS2; -.
DR   OrthoDB; 5241784at2; -.
DR   Proteomes; UP000272400; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR   Gene3D; 1.20.5.1930; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 2.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   PANTHER; PTHR24421:SF63; SENSOR HISTIDINE KINASE DESK; 1.
DR   Pfam; PF07730; HisKA_3; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ROO90928.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000272400};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..694
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017991208"
FT   TRANSMEM        27..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        60..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        350..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        374..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        400..419
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        439..459
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        466..487
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          508..573
FT                   /note="Signal transduction histidine kinase subgroup 3
FT                   dimerisation and phosphoacceptor"
FT                   /evidence="ECO:0000259|Pfam:PF07730"
SQ   SEQUENCE   694 AA;  70546 MW;  7D3768AEADB4FD1F CRC64;
     MTVVLVLLSF CAVYVLAAPS RAPGAWGAAL AIAAVLALFV LQLRHVLYRW PGPVPLALQV
     VLTFTAVLCL DVSVGLFGLL AGSLLLTEGR AAKAGALLMA SAAFPVAALR SGVGATALDS
     AVTAAIMALV VYGLTRLAAQ VEAVAAARLT AAGNAAAEER LRIAEELRGR LDAGLAALAR
     EAARPGPTAA SLGALLADAR AALAAVRTTA AEFRGLSLAP EVSAARTLLA AAGIEARVGV
     GHTEPLGATG SLLAAALREA VTRVVAEGTA RVCAIETEHR DGRVVLRVSD DGVRAAERPA
     SALDGLAERL RKAGGTLTSE LGADGRFTVE ASAPVTEGAL PSVDRASARL SVVLLATVLV
     GFCFKGLLQT PLYLMPYAVV LLVAVCAVQL GWMRGYRRTA SVLLLQGALS FLPLPWLGVS
     WVGAPGFFAG SLLIALPPAA AWSLTALVMA VVAGAAALLG QPAPVVVNLA VSVLVTGVVV
     RGLVLLARQV RELRAAGEGM ARAAALQERL RAARDLHDLL GHNLAAVLLK CEVAARLLEA
     DPPRARAELD AAAGLAERAR ADLRGAAGTA RTPLLVEELE SARAVLETAG IVVAVRDGGP
     VPDRTAAVLG PVLREAVTNV LKHGAAGRCE ITVASGPGPV RLEVASDGLD PAARPGPPGA
     GLGNLATRLA AQGGALSVSR DGRWFRLAAE LPPS
//