ID A0A3N1HLP5_9ACTN Unreviewed; 1427 AA.
AC A0A3N1HLP5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:ROP43396.1};
GN ORFNames=EDC03_2002 {ECO:0000313|EMBL:ROP43396.1};
OS Pseudokineococcus lusitanus.
OC Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC Pseudokineococcus.
OX NCBI_TaxID=763993 {ECO:0000313|EMBL:ROP43396.1, ECO:0000313|Proteomes:UP000276232};
RN [1] {ECO:0000313|EMBL:ROP43396.1, ECO:0000313|Proteomes:UP000276232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7306 {ECO:0000313|EMBL:ROP43396.1,
RC ECO:0000313|Proteomes:UP000276232};
RX PubMed=26203337; DOI=.1186/s40793-015-0017-x;
RA Whitman W.B., Woyke T., Klenk H.P., Zhou Y., Lilburn T.G., Beck B.J.,
RA De Vos P., Vandamme P., Eisen J.A., Garrity G., Hugenholtz P.,
RA Kyrpides N.C.;
RT "Genomic Encyclopedia of Bacterial and Archaeal Type Strains, Phase III:
RT the genomes of soil and plant-associated and newly described type
RT strains.";
RL Stand. Genomic Sci. 10:26-26(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROP43396.1}.
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DR EMBL; RJKN01000004; ROP43396.1; -; Genomic_DNA.
DR InParanoid; A0A3N1HLP5; -.
DR OrthoDB; 9805617at2; -.
DR Proteomes; UP000276232; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:ROP43396.1};
KW Hydrolase {ECO:0000313|EMBL:ROP43396.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000276232}.
FT DOMAIN 111..274
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 321..491
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 293..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 676..697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 680..695
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1427 AA; 155009 MW; 39A2466F51DC44E4 CRC64;
MAEQRTPSRR GSRRGGRPPG AGRAPAPVAD TPQTAALRAA LAEVGVADGQ RLERRLDGAL
RRPGPERGAA LERVAADVET ARERLAVRRT TVPAISYPPE LPVSGARDEI AAAIRDHQVV
VVAGETGSGK TTQLPKICLE LGRGARGMIG HTQPRRIAAR AVAERVAEEL AVPLGEQVGY
AVRFTDRVSD RTLVSVVTDG ILLAEVQRDP MLSRYDTVII DEAHERSLNI DFLLGILHRL
LPRRPDLKLV ITSATIDPRR FADHFADVAG EVPVIEVSGR TFPVEVRYRP LVDDTADADA
EEDDDEDDDR PARAAKEPVQ AVCDAVRELA ATGPGDVLVF LPGEREIRET ADAVARMQMR
GTEVLPLYAR LTGAEQHRVF SAHGPGVQRR VVLSTNVAET SLTVPGIRYV VDAGLARVSR
YSARLKVQRL PVEAVSQASA NQRSGRCGRV AEGVAIRLYS EADYEGRPRF TDPEVLRTSL
ASVILQMAAL GLGRVEDFPF VDPPDRRQVA DGLALLTELG AIETTEGDAA AERGPAEQRQ
LRLTPVGRRL ARLPLDPRLA RMVVEADRNS CVAEVLVLAA ALSVQDPRER PAEHQQAADA
AHARFRDERS DLLTLLALWR YLHAQQETLS SSAFRRMCKR EFLSWLRVRE WQDVHRQLRQ
LTRSLGVDAS SSAVLPDEDA DVVGEADDGD APEEDVLPGS EQQVDADRVH ASVLAGFLSS
IGMREERTKD PRAKVQAGRD AARPDRRERR NVEYLGARGA RFALWPGSVL ARKPPAWVMA
AELVETSRLW ARGVAAIQPE WVEALAGHLV RRTYSEPHWS KKRASVVASE RVLLHGLPLV
AARTIAYGRV DPVTSRDLFI RHALVEGDWV STHRFLDDNR ALLDEAEDLE HRTRTRGLVV
DEEALVAFYD ARVPADVVSG AHFDRWWKGE RRRRPDLLTF DPSALLADAA AGVQVDDFPL
LWRAGELDLR VSYRFAPGEE DDGATVHVPL RALAQLDPEP FAWQVPGLRH ELVTALVRGL
PKAVRRHLAP APDRAEAVLA VAGPADGPVL EVLSRELERL TGTPVPLADW DPAALPDHLR
VRFTVEDDDD RAADGSPRVL GTSRDLLALR RSLTADVRRA VSAAASDLER GGARDADAAF
ATGALPEEVS TAGVAGYPAL TDEGDAVAVR VYPTAGEARA AQRAGTLRLL RLELPTPGKD
VVRRLSNTDL LTLARSPHGS TAALLDDVWD AVLADLVRRA GGPPTDPEGH AALREQARTA
GPGAVAAAVG VVVRVLRSAA EVEERLGSLA DGAGAGLRAL AVRPALEDLR AQLAGLVHPR
MVTAAGLDRL PDLQRYLQGM LRRVASLPGD AARDRDRTGV VQRSAAEVEA AVAALPASRR
GDDDVREVRW TLEELRVSLF AQGLPTRGSV SPQRVTRALA ALPRDDG
//
