ID A0A3N1Q7N8_9MICO Unreviewed; 406 AA.
AC A0A3N1Q7N8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Threonine dehydrogenase-like Zn-dependent dehydrogenase {ECO:0000313|EMBL:ROQ37225.1};
GN ORFNames=EDF46_2679 {ECO:0000313|EMBL:ROQ37225.1};
OS Frondihabitans sp. PhB188.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Frondihabitans.
OX NCBI_TaxID=2485200 {ECO:0000313|EMBL:ROQ37225.1, ECO:0000313|Proteomes:UP000269803};
RN [1] {ECO:0000313|EMBL:ROQ37225.1, ECO:0000313|Proteomes:UP000269803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PhB188 {ECO:0000313|EMBL:ROQ37225.1,
RC ECO:0000313|Proteomes:UP000269803};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-V): Genome sequencing
RT to study the core and pangenomes of soil and plant-associated
RT prokaryotes.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROQ37225.1}.
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DR EMBL; RJUO01000004; ROQ37225.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N1Q7N8; -.
DR OrthoDB; 241504at2; -.
DR Proteomes; UP000269803; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR42813:SF7; ALCOHOL DEHYDROGENASE (ZN-DEPENDENT)-RELATED; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000269803};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 8..320
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 406 AA; 42424 MW; 5312BF515982CB0B CRC64;
MKAVVWHGVG NISLDSVADP TIQEPTDAIV EITRSAICGT DLHFIRGTMA GMNEGTILGH
EAVGVVREVG SSVRGFTAGD RVIINSTISC GVCRYCRVGQ TAQCDFANPN GPSAGTSFFG
GPAGTGPVNG LQAEFARVPF AQNTLTPIPD GVTDDQAILL SDIFPTSWFG AQLAGIRRGD
TVAVYGAGIV GQLAVASAFR QGASRVFAVD GIQTRLAVAL GQHAEVVDFN AEDPVEAIMD
ATRGMGVDAV IDAVGVDAQS PKSGPAAEAA AEQSDEFARE VEQVAPEQNT DGDNWIPGDA
PSQAAQWAVQ TVAKYGRVGI IGVYSPDMAS YPIGAAMNKN LTIRMGNCDH HSVTPPLVDL
VASGLFDPTA FITQDLPTTS AIDAYENFDR REEGWLKTVL EVKAAS
//
