ID A0A3N2ICX0_9MICO Unreviewed; 716 AA.
AC A0A3N2ICX0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
GN ORFNames=EDF38_3115 {ECO:0000313|EMBL:ROS58370.1};
OS Frigoribacterium sp. PhB160.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Frigoribacterium.
OX NCBI_TaxID=2485192 {ECO:0000313|EMBL:ROS58370.1, ECO:0000313|Proteomes:UP000280987};
RN [1] {ECO:0000313|EMBL:ROS58370.1, ECO:0000313|Proteomes:UP000280987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PhB160 {ECO:0000313|EMBL:ROS58370.1,
RC ECO:0000313|Proteomes:UP000280987};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-V): Genome sequencing
RT to study the core and pangenomes of soil and plant-associated
RT prokaryotes.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 42 family.
CC {ECO:0000256|ARBA:ARBA00005940}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROS58370.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; RKIE01000003; ROS58370.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N2ICX0; -.
DR OrthoDB; 9800974at2; -.
DR Proteomes; UP000280987; Unassembled WGS sequence.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd03143; A4_beta-galactosidase_middle_domain; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR013738; Beta_galactosidase_Trimer.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR003476; Glyco_hydro_42.
DR InterPro; IPR013529; Glyco_hydro_42_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR36447; BETA-GALACTOSIDASE GANA; 1.
DR PANTHER; PTHR36447:SF2; BETA-GALACTOSIDASE YESZ; 1.
DR Pfam; PF02449; Glyco_hydro_42; 1.
DR Pfam; PF08532; Glyco_hydro_42M; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000280987}.
FT DOMAIN 16..394
FT /note="Glycoside hydrolase family 42 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02449"
FT DOMAIN 408..624
FT /note="Beta-galactosidase trimerisation"
FT /evidence="ECO:0000259|Pfam:PF08532"
SQ SEQUENCE 716 AA; 78682 MW; B943D6C0F7DC47B5 CRC64;
MTSAPAHSGV LFGAAYYAEY QQAGTLDRDL DLMVEAGFTV IRVGESVWST WEPREGEFDL
DWLQPVLDGA HARGISVILG TPTYAVPPWL QVLHPEIAAE RTTGQRVGWG ARQEMDQSHP
AYRFYAERVV RRVAARYADH PAVVGWQVDN EPGNELPRND QVFARFVAWL ERRYGSVESL
NDEWGLVYWS HRLTEWSQLW RPDGNVQPQY DLEWRRFQGE LADELIAWQA DVVREYARDE
QFVTTCISYA RPQVADDRLV ESLDVTAGNP YYKMQDGLTR GVEVQREAGW WHTGVWALHQ
WGDRAFSSAQ APFLVTETNA QSIGGPWQNH PPFDGQIKQA ALALVARGAR MVEYWHWHTL
HFGVETYWGG VLPHSQRPGR IHREVAALGA TLKAVGGAVD GFLPASDVLM LWSTDTKWSF
EGYPPLALPD GGPDPDSYLH LFDAHYRGLA EAGAQVRIQH VAQFLATDPA TVAAEHPVLV
VPGLYVADDA TLEALAAYAE AGGHLVVGVR TGYGDELARA RRDVAPAVLS GPAGVWYEEY
TNLDEPLLVQ SADADADAPT IELEPGSAGT RWADVLVVEE AEVVLRFPAT EVGADAVMTT
RASGAGRVTY VATVPNPELS RSIARWLVPA TAVRAWAATD TVTVTTGSRP ESPDLAFVSN
WSAHEAAVTT PAAVRDLETR EVVAAGTAVT LAPRSAHVFE LVDDDQDDDD ATSVTP
//
