ID   A0A3N2M268_9BACT        Unreviewed;       632 AA.
AC   A0A3N2M268;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=PpiC domain-containing protein {ECO:0000259|PROSITE:PS50198};
GN   ORFNames=EEL33_16925 {ECO:0000313|EMBL:ROT03636.1};
OS   Muribaculaceae bacterium Isolate-037 (Harlan).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae.
OX   NCBI_TaxID=2486461 {ECO:0000313|EMBL:ROT03636.1, ECO:0000313|Proteomes:UP000275399};
RN   [1] {ECO:0000313|EMBL:ROT03636.1, ECO:0000313|Proteomes:UP000275399}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate-037 (Harlan) {ECO:0000313|Proteomes:UP000275399};
RA   Clavel T., Strowig T.;
RT   "Sequence and cultivation study of Muribaculaceae reveals novel species,
RT   host preference, and functional potential of this yet undescribed family.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ROT03636.1}.
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DR   EMBL; RIAZ01000027; ROT03636.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N2M268; -.
DR   Proteomes; UP000275399; Unassembled WGS sequence.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.50.40; -; 2.
DR   InterPro; IPR046357; PPIase_dom_sf.
DR   InterPro; IPR000297; PPIase_PpiC.
DR   InterPro; IPR023058; PPIase_PpiC_CS.
DR   PANTHER; PTHR47245:SF1; FOLDASE PROTEIN PRSA; 1.
DR   PANTHER; PTHR47245; PEPTIDYLPROLYL ISOMERASE; 1.
DR   Pfam; PF13616; Rotamase_3; 2.
DR   SUPFAM; SSF54534; FKBP-like; 2.
DR   PROSITE; PS01096; PPIC_PPIASE_1; 1.
DR   PROSITE; PS50198; PPIC_PPIASE_2; 2.
PE   4: Predicted;
KW   Isomerase {ECO:0000256|PROSITE-ProRule:PRU00278};
KW   Reference proteome {ECO:0000313|Proteomes:UP000275399};
KW   Rotamase {ECO:0000256|PROSITE-ProRule:PRU00278};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..632
FT                   /note="PpiC domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018083477"
FT   DOMAIN          115..215
FT                   /note="PpiC"
FT                   /evidence="ECO:0000259|PROSITE:PS50198"
FT   DOMAIN          220..321
FT                   /note="PpiC"
FT                   /evidence="ECO:0000259|PROSITE:PS50198"
SQ   SEQUENCE   632 AA;  70959 MW;  B5C1243D4685F2E1 CRC64;
     MRLFFVAGFA VASLCSIAKD PVVMTVDGKD VLKSEFEYLY HKNSRQQLEP QTIDDYVEMF
     KLYKRKVADA KACGIDTTAT FRDEMRQYRR ELAAPYLVDS TFIDALVQEA LLHSSEEVET
     SHIMLLKTKD GVKNRRNIQL LDSIRGAIAG GADFGDLAVK YSADGSAKTN RGNLGYIPYG
     RYPYMFETAA YNLPEGEVSE IVESPVGYHV LLGGKHRPAR GKVKVAHIMK MVPRDATDDA
     RYKSEIDSIY DVVTADPDKF QTLASELSDD KGSARQGGML PVFGPGEMVP EFEAVSYQLK
     PGETSHPFRS MYGWHIVKKY EDVAGPDADA IRKDVLKAIS NPRDDRYTLM KRNRTERLAA
     KHNASLNLPF VEELSETVYK DGGDGLAERY SGDSFWIAEI DGKRIPASEF IAGLKLSDNN
     AAGVDISAAA DSFFADALVN AEEDWLYENE TDYRNLLNEY HDGSLLYEVS LRKVWDKASK
     DTEGLERYFK EHRNDYKWDA PRAKGYLVLA SSDSVAAHLK KRLDGLAPDS VIPVVRKEFA
     GSAKIERMLV PKGVNATVDH LMFGAPEAKP QDSRYPISFV YQSRLIDSPE EMTDVKGQVT
     ADYQTQLENE WIEELKKKYP VKLNKGVLKK VK
//