ID   A0A3N2MG72_9BACT        Unreviewed;       359 AA.
AC   A0A3N2MG72;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 10.
DE   SubName: Full=3-methyl-2-oxobutanoate dehydrogenase subunit VorB {ECO:0000313|EMBL:ROT09158.1};
GN   Name=vorB {ECO:0000313|EMBL:ROT09158.1};
GN   ORFNames=EEL49_05090 {ECO:0000313|EMBL:ROT09158.1};
OS   Muribaculaceae bacterium Isolate-104 (HZI).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae.
OX   NCBI_TaxID=2486471 {ECO:0000313|EMBL:ROT09158.1, ECO:0000313|Proteomes:UP000266993};
RN   [1] {ECO:0000313|EMBL:ROT09158.1, ECO:0000313|Proteomes:UP000266993}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate-104 (HZI) {ECO:0000313|Proteomes:UP000266993};
RA   Clavel T., Strowig T.;
RT   "Sequence and cultivation study of Muribaculaceae reveals novel species,
RT   host preference, and functional potential of this yet undescribed family.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ROT09158.1}.
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DR   EMBL; RIBJ01000034; ROT09158.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N2MG72; -.
DR   OrthoDB; 9794954at2; -.
DR   Proteomes; UP000266993; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR033412; PFOR_II.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   PANTHER; PTHR43088; SUBUNIT OF PYRUVATE:FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   PANTHER; PTHR43088:SF1; SUBUNIT OF PYRUVATE:FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   Pfam; PF17147; PFOR_II; 1.
DR   Pfam; PF01855; POR_N; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000266993}.
FT   DOMAIN          15..194
FT                   /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT                   pyrimidine binding"
FT                   /evidence="ECO:0000259|Pfam:PF01855"
FT   DOMAIN          255..349
FT                   /note="Pyruvate:ferredoxin oxidoreductase core"
FT                   /evidence="ECO:0000259|Pfam:PF17147"
SQ   SEQUENCE   359 AA;  39407 MW;  08EF288166FB912F CRC64;
     MEEVRLMKGN EAIAHAAVRY GVDGYFGYPI TPQSEVLETL EALMPWETTG MVVLQAESEV
     AAINMVYGGA ATGKAVMTSS SSPGISLMAE GLSYIAAGEL PALVVNVMRG GPGLGTIHPS
     QADYFQATKG GGHGDYHFIV LAPSTVQEMA DFVGLGFDLA FKYRTPAMIL ADGIVGQMME
     KVVLPKPRPR RSDKEIARQC PWAVTGKPDS RKQNILTTLE LDSYKMEENN LRYQETYSII
     KRDEVRCEEC YTDDAEYLMV AFGSMARICL KAIEDARGNG IKVGLVRPIT LWPFPTENIE
     RLSRRVKGIL VVELNAGQMI EDVRMAAMGR IPVAHFGRLG GIVPNPQEVL DAFKERILK
//