ID A0A3N2NH68_9BACT Unreviewed; 616 AA.
AC A0A3N2NH68;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Aminopeptidase P family protein {ECO:0000313|EMBL:ROT21762.1};
GN ORFNames=EEL53_06505 {ECO:0000313|EMBL:ROT21762.1};
OS Muribaculaceae bacterium Isolate-114 (HZI).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae.
OX NCBI_TaxID=2486475 {ECO:0000313|EMBL:ROT21762.1, ECO:0000313|Proteomes:UP000273368};
RN [1] {ECO:0000313|EMBL:ROT21762.1, ECO:0000313|Proteomes:UP000273368}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate-114 (HZI) {ECO:0000313|Proteomes:UP000273368};
RA Clavel T., Strowig T.;
RT "Sequence and cultivation study of Muribaculaceae reveals novel species,
RT host preference, and functional potential of this yet undescribed family.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROT21762.1}.
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DR EMBL; RIBN01000008; ROT21762.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N2NH68; -.
DR Proteomes; UP000273368; Unassembled WGS sequence.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:ROT21762.1};
KW Hydrolase {ECO:0000313|EMBL:ROT21762.1};
KW Protease {ECO:0000313|EMBL:ROT21762.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000273368}.
FT DOMAIN 29..156
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 333..547
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 557..616
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 616 AA; 69601 MW; FDE8E55F3029DEEA CRC64;
MRIFVCKYVL DDKEKIRIQS HMKKNAQYLA NLRLAMKEHA IDCVIISGTD PHQSELPPMH
WRGREWLTGF ESENGTNGTA VVMSDKAYVW TDSRYFIQAT EQLRDTGFEM MKEDGPDAVN
LIDWVTEHLN TGQTVAIDGM TFSISWTQRL EQELNDNGIR LNDRFTPFDT IWTDRPERPK
NKLFVHDEKI VGETTDSKIT RLMQAVKGEL ANAILLSALD DIAWATNLRT AGDIAFSPIF
VAYLYVDDNR RILFIDKEKL SVEVDAHLSR YGIDVMPYDS VLDFAATLPK ETRLLIDPEK
TSRSLYDSLS CTPVFGGGDV AKLKSVKNAT MIENIKTAMR KDGVALTRFF MMAEREYPQG
KLTEVGLGKE LRALRLADAS CVDESFAPIL GWNEHGAIVH YEATEETDIP ITGNGLLLVD
SGGQYTYGTT DITRTIALGT PTAEQRHDFT LVLKGHIALS RAVFPKGTRG TQLDALARQY
LWAEGKAYYH GTGHGVGFFI NCHEGPQGIR LNDVPTPLEP GMILSNEPGL YLEGEYGIRT
ENLLAVEPFE TTRFGDFYRF ETLTLFPYDT SLIEKEIMTP EETEWVNAYH RKVYAELSPL
LDNEEQKWLA GKCKEI
//
