ID   A0A3N2NLY5_9BACT        Unreviewed;      1036 AA.
AC   A0A3N2NLY5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Efflux RND transporter permease subunit {ECO:0000313|EMBL:ROT23469.1};
GN   ORFNames=EEL53_02760 {ECO:0000313|EMBL:ROT23469.1};
OS   Muribaculaceae bacterium Isolate-114 (HZI).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae.
OX   NCBI_TaxID=2486475 {ECO:0000313|EMBL:ROT23469.1, ECO:0000313|Proteomes:UP000273368};
RN   [1] {ECO:0000313|EMBL:ROT23469.1, ECO:0000313|Proteomes:UP000273368}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate-114 (HZI) {ECO:0000313|Proteomes:UP000273368};
RA   Clavel T., Strowig T.;
RT   "Sequence and cultivation study of Muribaculaceae reveals novel species,
RT   host preference, and functional potential of this yet undescribed family.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ROT23469.1}.
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DR   EMBL; RIBN01000003; ROT23469.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N2NLY5; -.
DR   Proteomes; UP000273368; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   InterPro; IPR004763; CusA-like.
DR   NCBIfam; TIGR00914; 2A0601; 1.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF4; SLR6043 PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000273368};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        337..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        446..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        476..497
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        538..561
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        866..884
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        891..912
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        918..941
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        965..984
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        996..1020
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1036 AA;  113397 MW;  9E9B7E1C8164BF1A CRC64;
     MNFINRLIDF SLRNRLVILL AALLVIAGGV YTTKKMDVDV FPDLTAPTVV IMTDAKGMAS
     EEVERLVTFP IETAVNGATD VRRVRSASLQ GNSFVWVEFD WGTDIFKARQ IVSEKMVALG
     ESLPEGITPT LAPQSSVMGE ILFIGLQSDS TSMMELRTLA DWVIKPAILA TGGVSQVTNI
     GGELKQYQIL ADPQKMDFYG VTMEELEEVG KSFSVNSVGG VIRDYGNEYA LRGMGRTTDL
     EALGSTLVKT RNGKPVVLSD VAEVKTGAAV RMGNASQNGK PAVILSVSKQ PNINTLEVTE
     QIEENLEAIK KSLPSDVRMD TKIFRQADFI EASVNNVGRS LIEGAIFAVL ILFVFLASVR
     TTLISVIAIP LSLLGSCIIL YLMGMNINTM TLGGMCIAIG SLVDDAIIDV ENVYKRLRMN
     HALPKEDRLP VMKVVYEASK EIRSSILNAT FIIMVAFIPL FFLTGMEGRM LKPLGIAYIV
     ALFMSLIVAM TVTPLLCRMM LSGDRYLSKN EKESWMSRKL SSVYFKSLGW VLAHGKPVAI
     GTVIVFVVTI GLFMTMGSSF LPDFNEGSAT ISAVAKPGVS LEVNDKLGKM MEEALLEVPE
     VTATARRTGR GELDEHSQAT NGAEIDVQFN LKDRSRDEVF DDMRSRLAKI PGIAATIGQP
     LGHRIDHMLT GTRASIAIKI FGTDLSRMYM IGNNIKGYID EIPGAVDVSV EQQVETPQLQ
     IRANRDALAK YGITMDEFHK FVERAFSGDK IGDMYEGQRK FDIVLRLDKN YTEDIEGVKK
     ALIDTGNGRK VPLEEVADIV SAGGPNSISR ENVQRKLVVS ANVSGRDVVS VVEDIRKAVD
     ANIKLPEGYR IEYGGQFESA KNASRTLFFT TVLALMVIFL LLYSEFKNIS LAAIVLLNLP
     FALVGGVLAV YFTSGVVSIP VIIGFITLFG IATRNGILLI SKYQRLIKEG KTINETVLHG
     SIDRLNPILM TALTSALALI PLVFNGDKSG NEIQSPMAVV VLGGLLTSTL LNIYVMPIVY
     KWFVERKTVK NENKNQ
//