ID A0A3N2PE00_9ACTN Unreviewed; 380 AA.
AC A0A3N2PE00;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Acyl-CoA dehydrogenase {ECO:0000313|EMBL:ROT32847.1};
GN ORFNames=EF879_06590 {ECO:0000313|EMBL:ROT32847.1};
OS Micromonospora sp. HM5-17.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=2487710 {ECO:0000313|EMBL:ROT32847.1, ECO:0000313|Proteomes:UP000281230};
RN [1] {ECO:0000313|EMBL:ROT32847.1, ECO:0000313|Proteomes:UP000281230}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HM5-17 {ECO:0000313|EMBL:ROT32847.1,
RC ECO:0000313|Proteomes:UP000281230};
RA Thawai C.;
RT "Micromonospora sp. HM5-17, a new actinomycetes isolated from a hot spring
RT soil.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|RuleBase:RU362125};
CC -!- SIMILARITY: Belongs to the acyl-CoA dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009347, ECO:0000256|RuleBase:RU362125}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROT32847.1}.
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DR EMBL; RJWA01000002; ROT32847.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N2PE00; -.
DR OrthoDB; 3176804at2; -.
DR Proteomes; UP000281230; Unassembled WGS sequence.
DR GO; GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.540.10; Acyl-CoA dehydrogenase/oxidase, N-terminal domain; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR006089; Acyl-CoA_DH_CS.
DR InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR InterPro; IPR013786; AcylCoA_DH/ox_N.
DR InterPro; IPR037069; AcylCoA_DH/ox_N_sf.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR PANTHER; PTHR43884; ACYL-COA DEHYDROGENASE; 1.
DR PANTHER; PTHR43884:SF12; COMPLEX I ASSEMBLY FACTOR ACAD9, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00441; Acyl-CoA_dh_1; 1.
DR Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR Pfam; PF02771; Acyl-CoA_dh_N; 1.
DR PIRSF; PIRSF016578; HsaA; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
DR PROSITE; PS00072; ACYL_COA_DH_1; 1.
DR PROSITE; PS00073; ACYL_COA_DH_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU362125};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU362125};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU362125};
KW Reference proteome {ECO:0000313|Proteomes:UP000281230}.
FT DOMAIN 10..119
FT /note="Acyl-CoA dehydrogenase/oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02771"
FT DOMAIN 123..218
FT /note="Acyl-CoA oxidase/dehydrogenase middle"
FT /evidence="ECO:0000259|Pfam:PF02770"
FT DOMAIN 230..378
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
SQ SEQUENCE 380 AA; 41926 MW; AE4A11625E7FF532 CRC64;
MQQHLYEPVH DEFRDLCRAF LAREAVPYHD RWEADGIVDR EVWRRAGAAG LLGLDIPEEY
GGGGQHDFRF NAVLTEEIVA ANCSGLGFGL HNDVVAPYLR DLATEEARQR WLPGFCSGDL
ITAIAMTEPG AGSDLAGIRT TAVRDGDGYV LNGQKTFITN GELADLVVVV AKTDPERGPH
GVSLIAVERD TPGFTRGRRL AKVGLRANDT AELFFDDCWV PAANLVGTEN HGFYHLMANL
PRERLGIAVS AVAAAERLLA LTLEYVRSRE AFGRPVGSFQ HNRFLLAELD TEVTIARTFL
NHCVAEFVAG RLTPADAAKV KWWTTELRNR VADRCVQLHG GYGYMLEHPV ARSWLDGRVQ
TIYGGTTEIM KEIIGRDLGL
//
