ID A0A3N2PLD6_9PEZI Unreviewed; 530 AA.
AC A0A3N2PLD6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=RluA family pseudouridine synthase {ECO:0000313|EMBL:ROT35299.1};
GN ORFNames=SODALDRAFT_353031 {ECO:0000313|EMBL:ROT35299.1};
OS Sodiomyces alkalinus F11.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Sodiomyces.
OX NCBI_TaxID=1314773 {ECO:0000313|EMBL:ROT35299.1, ECO:0000313|Proteomes:UP000272025};
RN [1] {ECO:0000313|EMBL:ROT35299.1, ECO:0000313|Proteomes:UP000272025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F11 {ECO:0000313|EMBL:ROT35299.1,
RC ECO:0000313|Proteomes:UP000272025};
RX PubMed=30368956; DOI=10.1111/mec.14912;
RA Grum-Grzhimaylo A.A., Falkoski D.L., van den Heuvel J.,
RA Valero-Jimenez C.A., Min B., Choi I.G., Lipzen A., Daum C.G., Aanen D.K.,
RA Tsang A., Henrissat B., Bilanenko E.N., de Vries R.P., van Kan J.A.L.,
RA Grigoriev I.V., Debets A.J.M.;
RT "The obligate alkalophilic soda-lake fungus Sodiomyces alkalinus has
RT shifted to a protein diet.";
RL Mol. Ecol. 27:4808-4819(2018).
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DR EMBL; ML119061; ROT35299.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N2PLD6; -.
DR STRING; 1314773.A0A3N2PLD6; -.
DR OrthoDB; 5479603at2759; -.
DR Proteomes; UP000272025; Unassembled WGS sequence.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR CDD; cd02557; PseudoU_synth_ScRIB2; 1.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR006224; PsdUridine_synth_RluA-like_CS.
DR InterPro; IPR006225; PsdUridine_synth_RluC/D.
DR InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR NCBIfam; TIGR00005; rluA_subfam; 1.
DR PANTHER; PTHR21600; MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE; 1.
DR PANTHER; PTHR21600:SF40; PSEUDOURIDYLATE SYNTHASE RPUSD2; 1.
DR Pfam; PF00849; PseudoU_synth_2; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR PROSITE; PS01129; PSI_RLU; 1.
DR PROSITE; PS50889; S4; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000272025};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182}.
FT DOMAIN 200..381
FT /note="Pseudouridine synthase RsuA/RluA-like"
FT /evidence="ECO:0000259|Pfam:PF00849"
FT REGION 36..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 243
FT /evidence="ECO:0000256|PIRSR:PIRSR606225-1"
SQ SEQUENCE 530 AA; 59366 MW; 18242520D016CB3A CRC64;
MRRVQPAALN VTLAIVRRIA APLARFGNYL TSLMSPRPSS PSEATAPEPI DGAGVSPAKA
GAKVPNRPIA REISAHKKRL QALSETTHTI IPPCGDPWPR PYYFEDGLRK VKPYHFTYRT
YCKERWRGRT LLEVFECEFR AHTRTYYKQA IEAGRIVVNG RAVGSDYVLQ NGDLVNHTVH
RHEPPVTDEP ISVIHEDDGM LVVNKPAGVP VHPAGRYQFN SMTEILRSER GYHFNPRPCH
RLDRLTSGIL FFGKTAKAAD NLTEQIRQRT VRKEYLARVS GRFPDGEVVC DQPILQISPR
LGLNRVRANG KSARTVFKRL AYYPPLEDAD AEGRAGEGPG RETAEGAVNE KHRPWINNKG
HSIVRCLPLT GRTHQIRVHL QFLGHPIQND PLYANRRVWG FNLGCNDADG SEAKDEDIMS
RLERMGKDEV ADAVAYHDEM VQQYHERVAE KLSGEVCDVC HAELYTDPGD RELSIWLHSL
RYEDAGGKWS YVSPLPSWAL PPSGMSGPTE AGGMEDLVEA VKDENPEIAG
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