ID A0A3N2PY22_9PEZI Unreviewed; 2042 AA.
AC A0A3N2PY22;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Sec63 Brl domain-containing protein {ECO:0000313|EMBL:ROT39397.1};
GN ORFNames=SODALDRAFT_378496 {ECO:0000313|EMBL:ROT39397.1};
OS Sodiomyces alkalinus F11.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Sodiomyces.
OX NCBI_TaxID=1314773 {ECO:0000313|EMBL:ROT39397.1, ECO:0000313|Proteomes:UP000272025};
RN [1] {ECO:0000313|EMBL:ROT39397.1, ECO:0000313|Proteomes:UP000272025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F11 {ECO:0000313|EMBL:ROT39397.1,
RC ECO:0000313|Proteomes:UP000272025};
RX PubMed=30368956; DOI=10.1111/mec.14912;
RA Grum-Grzhimaylo A.A., Falkoski D.L., van den Heuvel J.,
RA Valero-Jimenez C.A., Min B., Choi I.G., Lipzen A., Daum C.G., Aanen D.K.,
RA Tsang A., Henrissat B., Bilanenko E.N., de Vries R.P., van Kan J.A.L.,
RA Grigoriev I.V., Debets A.J.M.;
RT "The obligate alkalophilic soda-lake fungus Sodiomyces alkalinus has
RT shifted to a protein diet.";
RL Mol. Ecol. 27:4808-4819(2018).
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DR EMBL; ML119054; ROT39397.1; -; Genomic_DNA.
DR STRING; 1314773.A0A3N2PY22; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000272025; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0010467; P:gene expression; IEA:UniProt.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd18020; DEXHc_ASCC3_1; 1.
DR CDD; cd18022; DEXHc_ASCC3_2; 1.
DR CDD; cd18795; SF2_C_Ski2; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF13; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 2.
DR Pfam; PF02889; Sec63; 2.
DR PIRSF; PIRSF039073; BRR2; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 2.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000272025}.
FT DOMAIN 285..478
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 509..712
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1144..1319
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1352..1561
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 26..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1908..1969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2016..2042
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2016..2030
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2042 AA; 226533 MW; C14015356809722F CRC64;
MAPNGLDAAE AQWRAQFEAM KSALAGLKLP PSDPSPLDFD DENEGYSSGN TAQDVWDFIS
VDDEDDYSSD YLDAPDVGPD GDAPYGAEWF VSKCSALAMK NGLSSDSLQN QIIGVLTAEQ
GDDGLQSQLT DLVGLDDLDF IIELLAHRSE IVTAATSRQI SVPEHSASKR ILTREEREEA
LRMQDYEHKN AALAPRFARE PQYPHVFKAH DAGNSLSHSG RKYALPQGSE RKLFDKYEEY
SIPAGKKTGL APGQTLVRIA DMDGLCRNTF KGYKTLNRMQ SLVHSVAYRT NENMLICAPT
GAGKTDAAML TILQTIGHYC TPNPIEDTAT TEFAVDMADF KIVYVAPMKA LAAEVTEKLG
TRLAWLGIKC REYTGDMHLT KSEIVQTQVI VTTPEKWDVV TRKGTGDTEL VQKVRLLIID
EVHMLHDERG AVLESLVART ERQVESTQSL IRIVGLSATL PNYIDVADFL KVNRYMGLFY
FDASFRPVPL EQHFIGVKGK AGSRQSKDNL DTVAFEKVRE MLQHGHQVMV FVHSRRDTLL
TAKMLHQKAT EDFCVDLFDP SGHPNYDNAL RDMKSSKARD LRELIPKGLG VHHAGMARSD
RNLIERLFGE GVIKVLCCTA TLAWGVNLPA AAVVIKGTQV YSAQDGKFVD LGILDVLQIF
GRAGRPQFED VGIGMICTTH DKLHHYLTAV TEQQPIESKF SSKLVDNLNA EIALGTVTSI
PEAVQWIGYS YLFVRMQRSP MAYGIEWAEI RDDPTLVQRR RKLAIQAART LQQCQMIIFN
EVTEELRSKD IGRIASQYYI LHTSIQVFNT MMQPQATEAD VLKMMSMSGE FDNIQSRDTE
SKELSHLRDN VPCAVDGGID TPQTKTNILL QAYISRAQPE DFALGNDLNY VAQQSGRICR
ALFMIALNRR WGHQCLVLLT LAKSIERRIW PFQHPLHQFN LPKPVLNNLD SKDSLSVEAM
RDMEPAEIGG LVHNHGAGKT IAKILNNFPT VSVEAEIAPL NRDVLRIKLY ITPDFRWNDQ
IHGTSESYYI WVENSETSEI YHHEFFILTR RKLNDDHELN FTIPLSDPLP TQIYVRAVSD
RWLGAETVTP VSFQQLIRPD TESFWTDLLD LQPLPVTALK NPALEEIYGQ RFQFFNPMQT
QIFHTLYHTP ANVLLGSPTG SGKTVAAELA MWWAFRERPG SKVVYIAPMK ALVRERVKDW
GARLAKPLGL KLVELTGDNT PDTRTIKDAD VIITTPEKWD GISRSWQTRG YVRQVSLVII
DEIHLLAGDR GPILEIIVSR MNYIAASTNN TVRLLGMSTA CANATDLGNW LGVKEGGLFN
FRHSVRPVPL EIYIDGFPEV RGFCPLMQSM NRPTFLAVKT HSPDKPVIVF VPSRRQTRLT
AKDLINLCGM EDDPRRFLHM NEDDLQLNLT RVKDDALKEA ISFGIGLHHA GLVESDRQLA
EELFLNNKVQ ILIATSTLAW GVNLPAHLVV VKGTQFYDAK IEGYRDMDLT DVLQMMGRAG
RPQFDNSGVA RIFTQDAKKD FYKHFLHKGF PVESSLHAVL DDHLCAEVSA ETVVTKQDAL
DYLTWTFFFR RLHKNPSYYG LEITAEDHNS VTAQRLANEF MIDMVDKSLA ELAKSKCVEV
YPNGDVDSTP LGKIMSYYYL SHRTIRYLAR HAAPRASFFD VLSWMSRAAE YDELPVRHNE
DLINAELSRN LPLPATNFGL PMWDPHVKAF LLLQAHFSRV SLPISDYIGD QTSVLDQAIR
IIQASIDVFA ELGYLSSCLQ MVTLLQCVKS ARWPTDPPAS ILPGFDLDDA ASKEDDKKKS
IPLATISATP NEKLSQLAAG LGVPRAKHAG FSKAVAALPN VAVSVPDGSV TSQGLSVELR
RLNRLTERDA RIFAPRFPKP QTEGWFVIVG DVANDEVMAV KRVGWGSGAY RGRNDQGKKG
KAGVGRGGAR GRGGRGGRGG RGGGGGGRIG GDGGSSGGGN AGGEGGLLVG ARPTARTTIK
LPESVQGRKL DVLVVSDAYI GLEYRVRGLD IPVPPTVDDD VDKEKGKGKA IVDGAAGGSG
SV
//
