ID A0A3N2Q8Y7_9PEZI Unreviewed; 853 AA.
AC A0A3N2Q8Y7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 08-NOV-2023, entry version 19.
DE RecName: Full=AdoMet-dependent rRNA methyltransferase SPB1 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=SODALDRAFT_253942 {ECO:0000313|EMBL:ROT43157.1};
OS Sodiomyces alkalinus F11.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Sodiomyces.
OX NCBI_TaxID=1314773 {ECO:0000313|EMBL:ROT43157.1, ECO:0000313|Proteomes:UP000272025};
RN [1] {ECO:0000313|EMBL:ROT43157.1, ECO:0000313|Proteomes:UP000272025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F11 {ECO:0000313|EMBL:ROT43157.1,
RC ECO:0000313|Proteomes:UP000272025};
RX PubMed=30368956; DOI=10.1111/mec.14912;
RA Grum-Grzhimaylo A.A., Falkoski D.L., van den Heuvel J.,
RA Valero-Jimenez C.A., Min B., Choi I.G., Lipzen A., Daum C.G., Aanen D.K.,
RA Tsang A., Henrissat B., Bilanenko E.N., de Vries R.P., van Kan J.A.L.,
RA Grigoriev I.V., Debets A.J.M.;
RT "The obligate alkalophilic soda-lake fungus Sodiomyces alkalinus has
RT shifted to a protein diet.";
RL Mol. Ecol. 27:4808-4819(2018).
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DR EMBL; ML119051; ROT43157.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N2Q8Y7; -.
DR STRING; 1314773.A0A3N2Q8Y7; -.
DR OrthoDB; 119516at2759; -.
DR Proteomes; UP000272025; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0008649; F:rRNA methyltransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_01547; RNA_methyltr_E; 1.
DR HAMAP; MF_03163; RNA_methyltr_E_SPB1; 1.
DR InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR InterPro; IPR015507; rRNA-MeTfrase_E.
DR InterPro; IPR012920; rRNA_MeTfrase_SPB1-like_C.
DR InterPro; IPR024576; rRNA_MeTfrase_Spb1_DUF3381.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR028589; SPB1-like.
DR PANTHER; PTHR10920:SF13; PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3; 1.
DR PANTHER; PTHR10920; RIBOSOMAL RNA METHYLTRANSFERASE; 1.
DR Pfam; PF11861; DUF3381; 1.
DR Pfam; PF01728; FtsJ; 1.
DR Pfam; PF07780; Spb1_C; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000272025};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 24..200
FT /note="Ribosomal RNA methyltransferase FtsJ"
FT /evidence="ECO:0000259|Pfam:PF01728"
FT DOMAIN 234..392
FT /note="DUF3381"
FT /evidence="ECO:0000259|Pfam:PF11861"
FT DOMAIN 641..851
FT /note="Ribosomal RNA methyltransferase SPB1-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF07780"
FT REGION 364..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 432..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..391
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..513
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 514..530
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..595
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 645..670
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 853
FT /evidence="ECO:0000313|EMBL:ROT43157.1"
SQ SEQUENCE 853 AA; 96367 MW; 8F34DACC3D752806 CRC64;
MAIQKKHGKG RLDKWYKLAK EKGYRARAAF KLIQLNKKYG FLEKSKVLLD LCAAPGSWCQ
VAAETMPINS LIIGVDLAPI KPIPKVITFQ SDITTDKCRA TIRQHLKTWK ADTVLHDGAP
NVGTAWNQDS FNQAELVLQS MKLATEFLVE GGTFVTKVFR SKDYNPLLWV FNQLFTKVEA
TKPPSSRNVS AEIFVVCTGY KAPKRMDPRF LDPRSVFAEL KGPAPNNEAK VYKPEVKKRK
REGYEEGDYT QFKEVPASEF IQTTDPLAIL GNVNRLSFKQ PQNGDVALAA MERLPETTDE
IRKCCEDLKV LGRGDFKLLL RWRLKVREIF GLATKATAEE PAAADEEVAE VEPMDEELRI
QEELQSLKEK EDAKKKRERR RENEKKQKEI VRMQLNMTVP MDIGMEQSGP MGEDAMFSLK
AVDKAGAAGR LARGKMAIPK QTEPSRDSGL GSSGETDSES DEEADLLERE LDSMYEQYRE
RKAAADAKYR AKRAREEHND DEFEGFSAEE GGKSEDEIDL EDDSSDESED EASDGKPLVT
DLQGAEEEGQ LSRRAKNFFS QDIFKDIPGL VEESEEEEDA KAKAKSKTKP NGDEEEIDDA
AIDAMIEAAS ANANNEAKSK KTEKKETAKQ QEKKQEGADE DEEDGGFEVV KRKDDDDWED
HDKRRPDGTL DIDIITAEAM TLAHQLATGQ KTSHEVIDEG FNRYSFRDRD GLPEWFVDDE
SKHDRPVKPI TKAAAMAIKE KLRAYNARPI KKVREAKARK KFKAAQRLEK LKKKSDMLIN
EESMTEKEKG EAISKMMAKA TKVTRRPKPT VVVAKGVNRG IKGRPKGVKG RYTILDPRMK
KDLRAQKRVT KKR
//
