ID A0A3N4ANU1_9PSED Unreviewed; 397 AA.
AC A0A3N4ANU1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Class I SAM-dependent rRNA methyltransferase {ECO:0000313|EMBL:ROZ85615.1};
GN ORFNames=EF099_04685 {ECO:0000313|EMBL:ROZ85615.1};
OS Pseudomonas sp. SSM44.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=2487347 {ECO:0000313|EMBL:ROZ85615.1, ECO:0000313|Proteomes:UP000268556};
RN [1] {ECO:0000313|EMBL:ROZ85615.1, ECO:0000313|Proteomes:UP000268556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SSM44 {ECO:0000313|EMBL:ROZ85615.1,
RC ECO:0000313|Proteomes:UP000268556};
RA Jang G.I., Hwang C.Y.;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmI family.
CC {ECO:0000256|ARBA:ARBA00038091}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROZ85615.1}.
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DR EMBL; RKKV01000003; ROZ85615.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4ANU1; -.
DR OrthoDB; 9805492at2; -.
DR Proteomes; UP000268556; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11572; RlmI_M_like; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR Gene3D; 3.30.750.80; RNA methyltransferase domain (HRMD) like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR041532; RlmI-like_PUA.
DR InterPro; IPR019614; SAM-dep_methyl-trfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR42873:SF1; METHYLTRANS_SAM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42873; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE; 1.
DR Pfam; PF10672; Methyltrans_SAM; 1.
DR Pfam; PF17785; PUA_3; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ROZ85615.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000268556};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ROZ85615.1}.
FT DOMAIN 6..72
FT /note="RlmI-like PUA"
FT /evidence="ECO:0000259|Pfam:PF17785"
FT DOMAIN 175..348
FT /note="S-adenosylmethionine-dependent methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF10672"
SQ SEQUENCE 397 AA; 44106 MW; 342626FC381E333D CRC64;
MTLPSLRLKH NSERRIRGGH LWVFSNEVDT AQTPLTELQL GQEVQLETST GKPLGLACVS
PNNLICARLH SRDTSHLLDK SLLVHRFKIA LSLRERLFGK PFYRLVYGES DLLPGLVIDR
FGDYFVVQIG TPGMERVRDD IVAALVQVFK PQAVLFKNDS GARKLEGLPS YVEDAFGTMP
ELVALEENGV AFQAPVRDGQ KTGWFYDHRN NRARLAPYVE GKRVLDLYSY IGGWGVQAAA
FGATEVMCVD SSAPALDRVE ANAELNGVAE KMVVVEGDVM TALKELKNAG ERFDVVIADP
PAFIKKRKDI RNGEAAYRRL NEQAMRLLNK DGILVSASCS MHLEEDKLKE ALLGASRHLD
RNLVITERGY QGADHPVHPA IPETAYIKAL FCRVTPV
//
