ID   A0A3N4H3D3_9BACT        Unreviewed;       938 AA.
AC   A0A3N4H3D3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE   AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN   Name=uvrA {ECO:0000313|EMBL:RPA67446.1};
GN   ORFNames=EF405_16450 {ECO:0000313|EMBL:RPA67446.1};
OS   Cyclobacteriaceae bacterium YHN15.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae.
OX   NCBI_TaxID=2487897 {ECO:0000313|EMBL:RPA67446.1, ECO:0000313|Proteomes:UP000274029};
RN   [1] {ECO:0000313|EMBL:RPA67446.1, ECO:0000313|Proteomes:UP000274029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YHN15 {ECO:0000313|EMBL:RPA67446.1,
RC   ECO:0000313|Proteomes:UP000274029};
RA   Chen Z.;
RT   "Cecembia caeni sp. nov.,isolated from a lake.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC       {ECO:0000256|ARBA:ARBA00038000}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RPA67446.1}.
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DR   EMBL; RKQB01000007; RPA67446.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N4H3D3; -.
DR   OrthoDB; 9809851at2; -.
DR   Proteomes; UP000274029; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR   Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR004602; UvrA.
DR   InterPro; IPR041552; UvrA_DNA-bd.
DR   InterPro; IPR041102; UvrA_inter.
DR   NCBIfam; TIGR00630; uvra; 1.
DR   PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR   PANTHER; PTHR43152:SF4; UVRABC SYSTEM PROTEIN A; 1.
DR   Pfam; PF17755; UvrA_DNA-bind; 1.
DR   Pfam; PF17760; UvrA_inter; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          254..589
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
FT   DOMAIN          601..934
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
SQ   SEQUENCE   938 AA;  104945 MW;  608F4EC0177B38F8 CRC64;
     MSLTYEMTLP AIDSLDPKEF IIIKNARVNN LKSLSVAIPR NKLIVITGLS GSGKSSLAFD
     TLFAEGQRMY VESLSSYARQ FLGRMEKPDV EYIKGVSPAI AIQQKVTNKN PRSTVGTSTE
     IYDYLKLLFS RIGKTISPVS GDEVKHHTVT DVVDFIHSFD EDEKVMITCP LHMLKGRTMQ
     QELELLLQKG FTRILVNGDP YFVEDFLGTE ELPNGDYEIL IDRAAIRHDD EDNLFRIADS
     VQTAFFEGHG DCTVFIPGKD KRAFSDRFEL DGMSFELPSV NFFSFNNPYG ACKTCEGFGS
     VLGIDPDLVI PDKSLSVYEG AIAPWRGETT GKWLEPLLKK GIYFDFPIHR AYEDLNDSEK
     ELLWSGNSHF KGLNEFFADL ESKTHKIQYR VMLSRFRGRT TCPDCKGTRL RKDASYVKIA
     EKSITDIVLM PIDKALRFFQ EIELVEAEKK IANRLLKEIL NRLEYIDKVG LGYLTLNRLT
     SSLSGGEYQR IKLATSIGSA LVGSMYILDE PSIGLHPRDS DRLIEVLKSL RDLGNTVIVV
     EHEEKIMKAA DQIIDIGPDA GVLGGELVFQ GDLKELLIKG NSYTAKYLKG EEKIHEKKQN
     RKWRDSIFIK GARENNLKNL SVRIPLHTLT VITGVSGSGK STLIKKVLYP ALGKLLGTVI
     DETGKFDKLE GDFKKITQLE FVDQNPIGKS SRSNPVTYVK AYDAIRTLYS DQTLAKQRGY
     KPAFFSFNVD GGRCEACQGE GTVTVEMQFM ADIHLTCESC KGKRFKNEIL DIKYQDKDIS
     EILGMTIDEA MEFFKGKPAI INKLQPLQEV GLGYIGMGQS SSTLSGGEAQ RVKLASFLVK
     GGTKPGDHVL FIFDEPTTGL HFHDIRKLLH SINALIEQGH SVIIIEHNTE VIKAADWVID
     LGPEGGEKGG NIVFEGTPEA LMEEEGNYTA KYLKESFQ
//