ID   A0A3N4H6M8_9BACT        Unreviewed;       740 AA.
AC   A0A3N4H6M8;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=S9 family peptidase {ECO:0000313|EMBL:RPA68688.1};
GN   ORFNames=EF405_08930 {ECO:0000313|EMBL:RPA68688.1};
OS   Cyclobacteriaceae bacterium YHN15.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae.
OX   NCBI_TaxID=2487897 {ECO:0000313|EMBL:RPA68688.1, ECO:0000313|Proteomes:UP000274029};
RN   [1] {ECO:0000313|EMBL:RPA68688.1, ECO:0000313|Proteomes:UP000274029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YHN15 {ECO:0000313|EMBL:RPA68688.1,
RC   ECO:0000313|Proteomes:UP000274029};
RA   Chen Z.;
RT   "Cecembia caeni sp. nov.,isolated from a lake.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC       pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RPA68688.1}.
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DR   EMBL; RKQB01000003; RPA68688.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N4H6M8; -.
DR   OrthoDB; 9812921at2; -.
DR   Proteomes; UP000274029; Unassembled WGS sequence.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR002469; Peptidase_S9B_N.
DR   PANTHER; PTHR11731:SF200; DIPEPTIDYL PEPTIDASE FAMILY MEMBER 2; 1.
DR   PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR   Pfam; PF00930; DPPIV_N; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          100..449
FT                   /note="Dipeptidylpeptidase IV N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00930"
FT   DOMAIN          538..735
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
SQ   SEQUENCE   740 AA;  84836 MW;  947F85351DC9A476 CRC64;
     MKYILFVFLF AFVGEVYSQS ELTLPDIYKN GVYRQNRFGP IRWMKDGSGY SSIEKSKKIE
     GDDIVRYDAL SGDRSILISA EELIPAGESK PLSVADYHWS EDNNKLLIFT NTRKVWRYHT
     RGDYWVLDLK SRKLSQLGKG IPATTLMFAK FSPDATKIAY VSENNIFVES LESGKITQIT
     ADGDKDIING TFDWVYEEEL ECRDGFRWSP DGENIAYWHS DTKGVGTFYL INNIDSIYSK
     PIPLPYPKVG HTLSAVKIGV VSASGGETKW FDFPGDPRNN YLARMEFIPN SQDVMVQQLN
     RRQNTNTVWT ANIQTMALSK VLVEEDDAFL DLHDNIRWLD GEKYFTWTSE RDGWLHLYKV
     SRDGKTVELV TEGGFDVERI SHIDPASGFV YYIASPDNFT QRYLYRSSLK KRGKAERITP
     LDLSGQNAYQ ISTDSRFAIH TFQNTTSPPV YSLVSLPNHK NIRVLEENQE LKQKYSDLGL
     KPKEFFKVDI GDVVLDGWMI KPKDFDPNKK YPLIAYVYGE PAGSTVQDAW MDGDLWHHYL
     ARLGYVVISI DNRGTKTPRG RDWRKSIYGQ IGILASYDQK AAVEKILQTY DFIDLSRVGS
     WGWSGGGQMT LNLMFRFPEI YKAGLALAFV SDQRLYDATY QERYMGLLED NEKGYIDGSP
     ITYAENLQGD LMVIHGTADD NVHYQSFEML VNKLIKFNKQ FSMMSYPMRA HGINERENTS
     LHLRETMKAF WLRSLPAGGR
//