ID   A0A3N4H7F0_9BACT        Unreviewed;       342 AA.
AC   A0A3N4H7F0;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 10.
DE   SubName: Full=NAD-dependent epimerase/dehydratase family protein {ECO:0000313|EMBL:RPA67591.1};
GN   ORFNames=EF405_14435 {ECO:0000313|EMBL:RPA67591.1};
OS   Cyclobacteriaceae bacterium YHN15.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae.
OX   NCBI_TaxID=2487897 {ECO:0000313|EMBL:RPA67591.1, ECO:0000313|Proteomes:UP000274029};
RN   [1] {ECO:0000313|EMBL:RPA67591.1, ECO:0000313|Proteomes:UP000274029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YHN15 {ECO:0000313|EMBL:RPA67591.1,
RC   ECO:0000313|Proteomes:UP000274029};
RA   Chen Z.;
RT   "Cecembia caeni sp. nov.,isolated from a lake.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RPA67591.1}.
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DR   EMBL; RKQB01000006; RPA67591.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N4H7F0; -.
DR   OrthoDB; 1490291at2; -.
DR   Proteomes; UP000274029; Unassembled WGS sequence.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48079; PROTEIN YEEZ; 1.
DR   PANTHER; PTHR48079:SF6; PROTEIN YEEZ; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          4..252
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
SQ   SEQUENCE   342 AA;  38244 MW;  519AF989C4B24F38 CRC64;
     MKILVTGGGG FLGFAIIRQL LSQGHEIVSF SRQQYPFLDE LGIIQYQGDL RDFDILKQAM
     EDCNAVFHVA AKMGMWGKFE DFFQTNVLGT ENVIKACKEQ GVRFLVFTSS PSVVFDGKDC
     EGKNESLPYP KRYNAYYPQT KAMAEQIVMA ANNPFFKTVC LRPHLIWGPG DNQLLPKLVE
     KAKNGRLRII GDGSNKVDCI FIDNAAIAHV LALDQITQDS SKVEGKAYFI SQGHPIAIAD
     LINQLLNAAG IPPVTKHLSP VISRVVAEAL ENIYRLFGIT SEPMITSFLS QQLITSHWYD
     ISAAKRDFGY RADVSIEKGM EQLKHWLSTE KTENIFPKSR GF
//