ID A0A3N4IF84_ASCIM Unreviewed; 697 AA.
AC A0A3N4IF84;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Acetoacetate-CoA ligase {ECO:0000313|EMBL:RPA83348.1};
GN ORFNames=BJ508DRAFT_360562 {ECO:0000313|EMBL:RPA83348.1};
OS Ascobolus immersus RN42.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Ascobolaceae; Ascobolus.
OX NCBI_TaxID=1160509 {ECO:0000313|EMBL:RPA83348.1, ECO:0000313|Proteomes:UP000275078};
RN [1] {ECO:0000313|EMBL:RPA83348.1, ECO:0000313|Proteomes:UP000275078}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RN42 {ECO:0000313|EMBL:RPA83348.1,
RC ECO:0000313|Proteomes:UP000275078};
RX PubMed=30420746; DOI=10.1038/s41559-018-0710-4;
RA Murat C., Payen T., Noel B., Kuo A., Morin E., Chen J., Kohler A.,
RA Krizsan K., Balestrini R., Da Silva C., Montanini B., Hainaut M.,
RA Levati E., Barry K.W., Belfiori B., Cichocki N., Clum A., Dockter R.B.,
RA Fauchery L., Guy J., Iotti M., Le Tacon F., Lindquist E.A., Lipzen A.,
RA Malagnac F., Mello A., Molinier V., Miyauchi S., Poulain J., Riccioni C.,
RA Rubini A., Sitrit Y., Splivallo R., Traeger S., Wang M., Zifcakova L.,
RA Wipf D., Zambonelli A., Paolocci F., Nowrousian M., Ottonello S.,
RA Baldrian P., Spatafora J.W., Henrissat B., Nagy L.G., Aury J.M.,
RA Wincker P., Grigoriev I.V., Bonfante P., Martin F.M.;
RT "Pezizomycetes genomes reveal the molecular basis of ectomycorrhizal
RT truffle lifestyle.";
RL Nat. Ecol. Evol. 2:1956-1965(2018).
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DR EMBL; ML119665; RPA83348.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4IF84; -.
DR STRING; 1160509.A0A3N4IF84; -.
DR Proteomes; UP000275078; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:RPA83348.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000275078}.
FT DOMAIN 46..101
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 110..498
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 697 AA; 76901 MW; 9BA968E12E8EA301 CRC64;
MVTAEPTPDS QLQALWRHPN PTQTEYYKFQ SHIEKKYSLS LNTPTSLWQW SVDNIPEFWA
EAWDYTGVVA SKRFDSVVDD QAPMFPRPQF FAGARLNFAE NLLFPKADVK EDGLAVVAAT
EEGRRSYTWK ELREEVRKCQ ASMEGRVKMG DRVVGYLGNG IHALVAMLAA TSLGCIWSGV
SPDTGPTAVL ERMEQLEPTI LFADNAVMYN GKVHNNMAKL TEVLAGLEKL GCLKSVVVVQ
TFGADTEFND SLSSLSLPGT EIISYDNYLG SGSPSHKLHF EQLEADTPIY ILFSSGTTGR
PKCICHGAIG TLLQHKKEHQ IHASMTSSSV FFQYTTITWM MWHWLVSGLA SGATIVLYDG
SPFRPNSHAS MPTLINELGV THFGTSAKYL SLLEQANLVP PPMPTLTTIF STASPLAPST
FTYIYKTFAP TVHLASITGG TDIISLFFTQ NPLLPLYPGQ IQDRGLGMAV HAAVGMTPDG
TLEEAEAGME GELVCTKPFP SMPVCFWGPN GLDQYRAAYF SPDDEFAGRV WKHGDFIRFH
PQTGGVEMLG RSDGVLNPAG VRFGSAELYG LLLREFSREI EDSVAVGRKK AGGDEDVVLF
VVVNPEWDPP YGSDWWEDLE ARVRSSIAKG LSLRHVPRWI IRAPEVPVTG NGKKVEVVVK
GIVNGKAKVG AAVVNGRCLE FYRQWAERLK REEEEAK
//
