ID A0A3N4KTQ7_9PEZI Unreviewed; 1053 AA.
AC A0A3N4KTQ7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=von Willebrand and RING finger domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=P167DRAFT_485308 {ECO:0000313|EMBL:RPB13943.1};
OS Morchella conica CCBAS932.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Morchellaceae; Morchella.
OX NCBI_TaxID=1392247 {ECO:0000313|EMBL:RPB13943.1, ECO:0000313|Proteomes:UP000277580};
RN [1] {ECO:0000313|EMBL:RPB13943.1, ECO:0000313|Proteomes:UP000277580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCBAS932 {ECO:0000313|EMBL:RPB13943.1,
RC ECO:0000313|Proteomes:UP000277580};
RX PubMed=30420746; DOI=10.1038/s41559-018-0710-4;
RA Murat C., Payen T., Noel B., Kuo A., Morin E., Chen J., Kohler A.,
RA Krizsan K., Balestrini R., Da Silva C., Montanini B., Hainaut M.,
RA Levati E., Barry K.W., Belfiori B., Cichocki N., Clum A., Dockter R.B.,
RA Fauchery L., Guy J., Iotti M., Le Tacon F., Lindquist E.A., Lipzen A.,
RA Malagnac F., Mello A., Molinier V., Miyauchi S., Poulain J., Riccioni C.,
RA Rubini A., Sitrit Y., Splivallo R., Traeger S., Wang M., Zifcakova L.,
RA Wipf D., Zambonelli A., Paolocci F., Nowrousian M., Ottonello S.,
RA Baldrian P., Spatafora J.W., Henrissat B., Nagy L.G., Aury J.M.,
RA Wincker P., Grigoriev I.V., Bonfante P., Martin F.M.;
RT "Pezizomycetes genomes reveal the molecular basis of ectomycorrhizal
RT truffle lifestyle.";
RL Nat. Ecol. Evol. 2:1956-1965(2018).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ML119120; RPB13943.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4KTQ7; -.
DR STRING; 1392247.A0A3N4KTQ7; -.
DR InParanoid; A0A3N4KTQ7; -.
DR Proteomes; UP000277580; Unassembled WGS sequence.
DR CDD; cd16448; RING-H2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR Pfam; PF15411; PH_10; 1.
DR Pfam; PF13768; VWA_3; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000277580};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 23..69
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 543..716
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 70..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..294
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1053 AA; 117378 MW; CC1473BB4220BF69 CRC64;
MAGMLDMDRG RSRRDRTFVG SHCAACEEPL EHTLRGERIL QFSCSHVAHE ACFYEYIKEV
DSQYCPECHA PLGLDTSRGG NVLDIGSERE RERERERERE REGERERERE RERERERERE
RDLASPQYEN YGSRARSRQG SRTSSLNRDG RAESRNETRD SSQRQHDSGH WRNNSGTSVS
ASEGYADPNS AAAPVRRHDY DIQSMESELS PRNSMANPIH PPTVTVKSEF PTLTRSKVQQ
SLTCLVTIEV PQRKWQPMYN EEVPPIPSLP AAYDQQYQPP SPTGRSQYSF ERESSSTRQQ
REREAERERE LEALASITED LRLRVENWHG LDFARFGKLR LHGTIRVGKD CQAWQELECY
LFSEMLICVK EKKVSSSASQ WSNGQKKIRA VKCTLKGSIL IKKHLKKVND SSNRGTSLSA
FTLNDNMHIL TLNLSVAELP QFHLLFPNHA QLDQWQRALL DLNSVDPAPS RSPQYDEKVQ
SISDVDDDDY RTMKTTRRVS SVNSTYSGGH GGSRSVVTAP TEYTASIRGG RQNIPQSMHI
PLDVVVVIPV SSSMQGLKIN LLRDALKFLV QNLGERDRMG LVSFGSSSGG VPLTSLLAKN
WTGWGKAIHS IRPVGQKTLR TDVVDGANVA MDLLMQRKSS NPIASILLIS DSSTSETENV
DFVVSRAEAA KITIHSFGLG LTHKPDTIME MSTRTKGQYT YVKDWMMLRE CVAGCVGSLQ
TLSHQNAKLK LKLPEGSPAR FHKISGALHV SKRATGREAE ASLGDLHFGD KKDILVQLVI
SPDNSQGDTA PQDAWESIVS GLEALGGSTD QDEQRTVSIE EVPLILADLT FGDLQRDGTL
SQLSRPHLLA ITMLPPSNSK KTGRPGSPPI PPHPMVVQRR MELLTSDMLS RALVLVSRNQ
HDHAQKLLSE TRTILKGLGK GGLPPLPAPS PNMPLPELPE GAVSLSNLHQ QTFTATPPLE
HIFTPATGID PTTVSALDAE LESALEWIGH PAVFARDSRK AVLQAIGVIS SQRAITFRTA
CESLYSERIP GVKRLSVQAR EWRDTEDSLM EED
//
