ID A0A3N4L1Y4_9PEZI Unreviewed; 368 AA.
AC A0A3N4L1Y4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=VHS domain-containing protein {ECO:0000259|PROSITE:PS50179};
GN ORFNames=P167DRAFT_531773 {ECO:0000313|EMBL:RPB16833.1};
OS Morchella conica CCBAS932.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Morchellaceae; Morchella.
OX NCBI_TaxID=1392247 {ECO:0000313|EMBL:RPB16833.1, ECO:0000313|Proteomes:UP000277580};
RN [1] {ECO:0000313|EMBL:RPB16833.1, ECO:0000313|Proteomes:UP000277580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCBAS932 {ECO:0000313|EMBL:RPB16833.1,
RC ECO:0000313|Proteomes:UP000277580};
RX PubMed=30420746; DOI=10.1038/s41559-018-0710-4;
RA Murat C., Payen T., Noel B., Kuo A., Morin E., Chen J., Kohler A.,
RA Krizsan K., Balestrini R., Da Silva C., Montanini B., Hainaut M.,
RA Levati E., Barry K.W., Belfiori B., Cichocki N., Clum A., Dockter R.B.,
RA Fauchery L., Guy J., Iotti M., Le Tacon F., Lindquist E.A., Lipzen A.,
RA Malagnac F., Mello A., Molinier V., Miyauchi S., Poulain J., Riccioni C.,
RA Rubini A., Sitrit Y., Splivallo R., Traeger S., Wang M., Zifcakova L.,
RA Wipf D., Zambonelli A., Paolocci F., Nowrousian M., Ottonello S.,
RA Baldrian P., Spatafora J.W., Henrissat B., Nagy L.G., Aury J.M.,
RA Wincker P., Grigoriev I.V., Bonfante P., Martin F.M.;
RT "Pezizomycetes genomes reveal the molecular basis of ectomycorrhizal
RT truffle lifestyle.";
RL Nat. Ecol. Evol. 2:1956-1965(2018).
CC -!- SUBUNIT: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
CC {ECO:0000256|ARBA:ARBA00011446}.
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DR EMBL; ML119107; RPB16833.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4L1Y4; -.
DR STRING; 1392247.A0A3N4L1Y4; -.
DR InParanoid; A0A3N4L1Y4; -.
DR Proteomes; UP000277580; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProt.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR CDD; cd14232; GAT_LSB5; 1.
DR CDD; cd16980; VHS_Lsb5; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR044103; GAT_LSB5.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR045007; LSB5.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR47789; LAS SEVENTEEN-BINDING PROTEIN 5; 1.
DR PANTHER; PTHR47789:SF1; LAS SEVENTEEN-BINDING PROTEIN 5; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000277580}.
FT DOMAIN 1..120
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT REGION 112..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..368
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 368 AA; 41138 MW; E0A08E577E686D80 CRC64;
MSGIPELIES IKLQDTGPTE ASRAIRKKLK YGNVHRQLRA LTILDALIGN AGIRFQRSFA
DEPLLERLRI AATDLMTDPD VKAKLKVVFG QWAVAYKDTQ GLQSIASLYK QLPQRQRPRP
QPKVLSEVPA DNDREPSSST GRKATPTSPK SPKPTPITLG QSADLGVGQK GHKKSSSKSK
SKTPPFSLEK EKPAMLQSLA NASVASTNLK NALKLINREK ERPSGNPEVL KRFEDCRALR
RSILRYIQHV ESEQWLGGLI HANEELVEAL TLYEVLDKPI EEDSDSEDEG WNDPPDRSVD
SVSQGFGNMR MHDGEENRPS MPPRPGMAKG KSTAYESEPV EEQDEEDPDD PFGDNQYRIE
EPEDKRPW
//
