ID A0A3N4LRL3_9PEZI Unreviewed; 891 AA.
AC A0A3N4LRL3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Probable endonuclease LCL3 {ECO:0000256|ARBA:ARBA00013404};
DE AltName: Full=Probable endonuclease lcl3 {ECO:0000256|ARBA:ARBA00014651};
GN ORFNames=L211DRAFT_785307 {ECO:0000313|EMBL:RPB24328.1};
OS Terfezia boudieri ATCC MYA-4762.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Pezizaceae; Terfezia.
OX NCBI_TaxID=1051890 {ECO:0000313|EMBL:RPB24328.1, ECO:0000313|Proteomes:UP000267821};
RN [1] {ECO:0000313|EMBL:RPB24328.1, ECO:0000313|Proteomes:UP000267821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4762 {ECO:0000313|EMBL:RPB24328.1,
RC ECO:0000313|Proteomes:UP000267821};
RX PubMed=30420746; DOI=10.1038/s41559-018-0710-4;
RA Murat C., Payen T., Noel B., Kuo A., Morin E., Chen J., Kohler A.,
RA Krizsan K., Balestrini R., Da Silva C., Montanini B., Hainaut M.,
RA Levati E., Barry K.W., Belfiori B., Cichocki N., Clum A., Dockter R.B.,
RA Fauchery L., Guy J., Iotti M., Le Tacon F., Lindquist E.A., Lipzen A.,
RA Malagnac F., Mello A., Molinier V., Miyauchi S., Poulain J., Riccioni C.,
RA Rubini A., Sitrit Y., Splivallo R., Traeger S., Wang M., Zifcakova L.,
RA Wipf D., Zambonelli A., Paolocci F., Nowrousian M., Ottonello S.,
RA Baldrian P., Spatafora J.W., Henrissat B., Nagy L.G., Aury J.M.,
RA Wincker P., Grigoriev I.V., Bonfante P., Martin F.M.;
RT "Pezizomycetes genomes reveal the molecular basis of ectomycorrhizal
RT truffle lifestyle.";
RL Nat. Ecol. Evol. 2:1956-1965(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR017179}.
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DR EMBL; ML121542; RPB24328.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4LRL3; -.
DR STRING; 1051890.A0A3N4LRL3; -.
DR InParanoid; A0A3N4LRL3; -.
DR Proteomes; UP000267821; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016442; C:RISC complex; IEA:UniProtKB-UniRule.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:InterPro.
DR CDD; cd00175; SNc; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.40.50.90; -; 5.
DR InterPro; IPR016685; Silence_cplx_Nase-comp_TudorSN.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR016071; Staphylococal_nuclease_OB-fold.
DR InterPro; IPR002999; Tudor.
DR PANTHER; PTHR12302; EBNA2 BINDING PROTEIN P100; 1.
DR PANTHER; PTHR12302:SF2; STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00565; SNase; 4.
DR Pfam; PF00567; TUDOR; 1.
DR PIRSF; PIRSF017179; RISC-Tudor-SN; 1.
DR SMART; SM00318; SNc; 4.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF50199; Staphylococcal nuclease; 5.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50830; TNASE_3; 4.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR017179};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022759};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000267821};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 2..148
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 174..309
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 319..456
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 485..618
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 706..766
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 617..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 891 AA; 98818 MW; 6E8E2D12F3D638F9 CRC64;
MSANIAIVKS AVSGDSVVLL STMTPPPGEP PLEKTLSFAF VSAPRLKREG DEPYAFQSRE
HLRKLIVGKE VQFGVLHTVP SGSSQRDYGL ITLPTGESVI EQMVSEGLVK VREEAGGRDE
GEDIEILIEK LKILQNQAML EGKGRWSTVD DGRIETGDGP LADPAAFLEQ WKGKRVEAVI
ERIISGDRVA VRLLLEPKSH RQVVVLIAGI RCPRSDGNEA GEEFGEEAKS FSEFRLLQRT
VHVELLDLTP QNQLIGIISH AKGNIAEHLL LEGLARCNDF HSTILGARMA RLRAAEQRAK
DERLKMWKGH VVKKLDNTNS FDAVVSRIIW ADQLIIRNKA GQEKKVSLSS VRGPKNTDPK
QSPWQAEAKE FLRRKIIGKH VRVAIDGKRP ASEGYEEREM ATVMFGDKNI ALGLVEAGLA
SVIRHRRDDE DRSPIYDELL AADEQAQASS VGMYSNKAPA TAKITEASES LQKAKTYLSF
LQRQKRIPAV VDYCAAGSRF KVIIPRENAR ITFILGGIRA PKTARNANET SEPFGQEALD
FVSKKVMQRD VEIDVENIDR VGGFIGTMFI GRENVAKLLV VEGLASVHAY SAGQSPHGSD
LFAAEKLAQD AKKGMWHNYD PSQEASQEAS LDTLTISTPP NGASTTPQEK RKDYKDVLVT
HVDPETCALK LHVLTGDLGP SPLESFMAEF RTYHASSANA IPLQNLPRNG EYVAAKFTED
NTFYRARVRA VDREAKTCEV VYIDYGNSER IPLTRLRALA PQHHPTTGKL KAQAQDAVFS
FVEFSKNKEY LGDAVHFVQD MTGGDRPLVA NVDWIDEKEG GVWYVTLYDP KESKSAEASL
NADIVREGMA IAGRKERGFE KAWPEVIKTV REKEDEAKKE RLGMWEYGGE Y
//
