ID A0A3N4LVV8_9PEZI Unreviewed; 449 AA.
AC A0A3N4LVV8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:RPB25322.1};
GN ORFNames=L211DRAFT_856825 {ECO:0000313|EMBL:RPB25322.1};
OS Terfezia boudieri ATCC MYA-4762.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Pezizaceae; Terfezia.
OX NCBI_TaxID=1051890 {ECO:0000313|EMBL:RPB25322.1, ECO:0000313|Proteomes:UP000267821};
RN [1] {ECO:0000313|EMBL:RPB25322.1, ECO:0000313|Proteomes:UP000267821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4762 {ECO:0000313|EMBL:RPB25322.1,
RC ECO:0000313|Proteomes:UP000267821};
RX PubMed=30420746; DOI=10.1038/s41559-018-0710-4;
RA Murat C., Payen T., Noel B., Kuo A., Morin E., Chen J., Kohler A.,
RA Krizsan K., Balestrini R., Da Silva C., Montanini B., Hainaut M.,
RA Levati E., Barry K.W., Belfiori B., Cichocki N., Clum A., Dockter R.B.,
RA Fauchery L., Guy J., Iotti M., Le Tacon F., Lindquist E.A., Lipzen A.,
RA Malagnac F., Mello A., Molinier V., Miyauchi S., Poulain J., Riccioni C.,
RA Rubini A., Sitrit Y., Splivallo R., Traeger S., Wang M., Zifcakova L.,
RA Wipf D., Zambonelli A., Paolocci F., Nowrousian M., Ottonello S.,
RA Baldrian P., Spatafora J.W., Henrissat B., Nagy L.G., Aury J.M.,
RA Wincker P., Grigoriev I.V., Bonfante P., Martin F.M.;
RT "Pezizomycetes genomes reveal the molecular basis of ectomycorrhizal
RT truffle lifestyle.";
RL Nat. Ecol. Evol. 2:1956-1965(2018).
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DR EMBL; ML121538; RPB25322.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4LVV8; -.
DR STRING; 1051890.A0A3N4LVV8; -.
DR InParanoid; A0A3N4LVV8; -.
DR Proteomes; UP000267821; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1870.10; Domain 3, Saccharopine reductase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032095; Sacchrp_dh-like_C.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR11133:SF25; ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR Pfam; PF16653; Sacchrp_dh_C; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW Lysine biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000267821}.
FT DOMAIN 6..120
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
FT DOMAIN 124..442
FT /note="Saccharopine dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16653"
SQ SEQUENCE 449 AA; 49687 MW; D80F3381C461EF9A CRC64;
MSTHKVLLLG SGFVAKPCLD ILVKTGIQVT VACRTVETAR KLVGELEGVS PIALDVEDTA
VLDAEVAKHD LVVSLIPYIH HPIVIKSAIR NKKHVVTTSY VSRAMMELDA QAKAAGITVM
NEIGLDPGID HLYAVKMIDE VHAAGGKIIS FLSYCGGLPA PEDSDNPLGY KFSWSSRGVL
LALRNSAKYW KDGKIEEISG PKLMEAAKPY FIYPGYAFIA YPNRDSTEYR ERYNIPEAET
IIRGTLRYQG FAEFIKAFVD LGFLDDTPVE FLTKTSQPLT WKETVARTLR IESTIEEDLI
YAISKATTFS NEAEKIRVIN GLRWVGFFSD EKVTPRGNLL DTLCATLEAK MQYGPNERDL
VMLQHKFEIE LADGKRETRT STLVDYGIPG GYSSMAKLVG VPCGVAVKQI LNGTITDRGV
LAPMNVKLNN PLIKELKEEY GIECIEKTI
//
