ID A0A3N4M4J2_9PEZI Unreviewed; 1260 AA.
AC A0A3N4M4J2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=L211DRAFT_864495 {ECO:0000313|EMBL:RPB28809.1};
OS Terfezia boudieri ATCC MYA-4762.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Pezizaceae; Terfezia.
OX NCBI_TaxID=1051890 {ECO:0000313|EMBL:RPB28809.1, ECO:0000313|Proteomes:UP000267821};
RN [1] {ECO:0000313|EMBL:RPB28809.1, ECO:0000313|Proteomes:UP000267821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4762 {ECO:0000313|EMBL:RPB28809.1,
RC ECO:0000313|Proteomes:UP000267821};
RX PubMed=30420746; DOI=10.1038/s41559-018-0710-4;
RA Murat C., Payen T., Noel B., Kuo A., Morin E., Chen J., Kohler A.,
RA Krizsan K., Balestrini R., Da Silva C., Montanini B., Hainaut M.,
RA Levati E., Barry K.W., Belfiori B., Cichocki N., Clum A., Dockter R.B.,
RA Fauchery L., Guy J., Iotti M., Le Tacon F., Lindquist E.A., Lipzen A.,
RA Malagnac F., Mello A., Molinier V., Miyauchi S., Poulain J., Riccioni C.,
RA Rubini A., Sitrit Y., Splivallo R., Traeger S., Wang M., Zifcakova L.,
RA Wipf D., Zambonelli A., Paolocci F., Nowrousian M., Ottonello S.,
RA Baldrian P., Spatafora J.W., Henrissat B., Nagy L.G., Aury J.M.,
RA Wincker P., Grigoriev I.V., Bonfante P., Martin F.M.;
RT "Pezizomycetes genomes reveal the molecular basis of ectomycorrhizal
RT truffle lifestyle.";
RL Nat. Ecol. Evol. 2:1956-1965(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; ML121528; RPB28809.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4M4J2; -.
DR STRING; 1051890.A0A3N4M4J2; -.
DR InParanoid; A0A3N4M4J2; -.
DR Proteomes; UP000267821; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF72; GH08340P; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000267821};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 85..526
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 538..621
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 646..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..1153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 941..955
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1013..1037
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1103..1117
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1260 AA; 137536 MW; 29DBF21601B0A0DC CRC64;
MGFVLESVLG VVGCYRLVNE CVVLAVLGLR ADHAECPVHS YVLTFWLYFG AERDSGNIGY
AGCKVYLQHK PPNGSVINST KVDASYFVCL ITTLSISAIS SNGTVRGGGA YYLISRSLGP
EFGGSIGLVF YMGCVFNTGL NAVGMVDCLV NNFGEVSGTS HQVLPEDYWM RYLYATGVLV
LCTVICMMGS SIFAKASNFL LIFLLAATFA IPLSAVIREP FYDPNLDISF TGLSMKTLKD
NLFPRFNKEA AGSGSPEGES FQDLFGILFP ACSGIFAGAS MSGDLRKPSK SIPKGTLHGL
LWTFLTYTLV ILAMGASITR DSMYNDLNII QDTNISGPLI LLGEFATSFF SALMGVIGSA
KSLQALARDD LLPGFSFLAQ GTKSNDEPIV AILVTFILSQ LTLVCDINQI ASFITMTYLM
TFFATNLACF LLKISSAPNF RPSFKYFTAW TAFVGAVISC IIMFFVDGVY ATGCVGILGT
LFLIVHYTTP PKSWGDVSQS LIYHQVRKYL LRLKQEHVKF WRPQILLFVN DPRNSWELIQ
FCNSLKKGGL YILGHIIVTS DFQDSFAEVK RQQAAWMKYI DFSKIKGFVQ IAIAPTVEWG
ARNIVLSAGL GGMHPNIAVL GLYNLSEYRA SRPLVDIPSL PLSQAGSNAP SIKPGKKDKK
GSIRIPDAGE LPTDSCRPEK AVTPQSYVNI LEDLLLSLQI NVAIAKGFKD LELPDKDDHK
HGETKKKFID LWPIQMAAEI EGDSKDKASG LLTTNFDTYT LILQLGCILH TVPSWKKYYS
VRVIVFVEYE SEVEEEQQRV AKLLENLRIQ AEIIVTYLAN GSLKCYETIV NGSPNENPIV
DAVLGKEDWW KELKQRRRRG NAPRNVTDIS TLFRSTDNLS RIGSFQQGST KGRWEVRLGS
LGKFVNKKKR HTMGGLNRLG MPFSLTMRAN RLRSEVLTSD SELSDTEDEG EGSSEESSES
AVSEGDLSDY QERGQADNSQ LGEIVRGVRQ RRASTGDALG QLLRKNNSHR HTKVPSQSHT
PAQKQTSNPT TPLLAPQLQH QDPGKPQLQP LHLQPPLATP QKLKRPDFIH RKSTPSFTSR
PVPEPEISLS EEPGAPSIGF SSAAHSPAGT LPSTPVTAQG VKVKREGKPK AGSHLADPPM
TPSNANTPSP APAAAAGVTI SFNDLPSKAQ HLILNELMRQ YSGQKREENV VGYGSIGTGE
GRNGGSKTAV MFTTLPAPVG GTWRSEKESL EYLGGLELLT GGLPPTVLVH SNSLTVTTAL
//
