ID A0A3N4RIE7_9ACTN Unreviewed; 588 AA.
AC A0A3N4RIE7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:RPE33162.1};
GN ORFNames=EDD38_1441 {ECO:0000313|EMBL:RPE33162.1};
OS Kitasatospora cineracea.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=88074 {ECO:0000313|EMBL:RPE33162.1, ECO:0000313|Proteomes:UP000266906};
RN [1] {ECO:0000313|EMBL:RPE33162.1, ECO:0000313|Proteomes:UP000266906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44781 {ECO:0000313|EMBL:RPE33162.1,
RC ECO:0000313|Proteomes:UP000266906};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPE33162.1}.
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DR EMBL; RKQG01000001; RPE33162.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4RIE7; -.
DR Proteomes; UP000266906; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 9..331
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 384..488
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 510..564
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 155
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 231
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 588 AA; 64585 MW; 7FD30853A86122EE CRC64;
MLTYDSNGFR LDGRPLRILS GAVHYFRSRP EQWPDRLAAV RAMGLNTVET YVPWNLHEPA
PGRFTRLDEL GAFLDEAHRQ GLWTIVRPGP YICAEWDNGG LPGWLTARVG RRARTSDPGF
LAAVDAFFDV LLPQVVERQW GRPGGTVLMV QVENEYGAHG SDADYLAHLA RGLRERGITV
PLFTSDGPED HMLAAGTVPG VLATVNFGSD PEGAFAALRR HRPEDPPFCM EYWNGWFDRW
GGPHHTRDAG DAADALRRIL AAGGSVNLYM AHGGTNFGTT AGANHADPPF NSTDWTHSPY
QPITTSYDYD APLDERGLPT AKFDAFRQVI ADFAAEHPEL ARYLDHREPE LPAPAPVLDA
REVLLDEYAE LPFGPAVHSP VPPLFEELGL EHGLVRYTTT VPDRSPDLPL TVEGLHDRAT
LHLDGKPAAT LERGVAPEPV TAGGGTRIRL LVESLGRVNY GPQVGETKGL TGVRHERQYL
HGWQAEPLPL APLPTPAWTP GTPAPELLAR GTLHLDAPGD TFLTVPEGEH GYLWVNDFLL
GRYDTRGPQH TLYCPWPLLR PGPNTLTLLE LGPTTPSRIH LHPSPDLG
//
