ID A0A3N4RIF8_9ACTN Unreviewed; 340 AA.
AC A0A3N4RIF8; A0A8G1U987;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Ketopantoate reductase {ECO:0000313|EMBL:RPE26900.1};
GN ORFNames=EDD38_7537 {ECO:0000313|EMBL:RPE26900.1}, EDD39_7651
GN {ECO:0000313|EMBL:ROR34090.1};
OS Kitasatospora cineracea.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=88074 {ECO:0000313|EMBL:RPE26900.1, ECO:0000313|Proteomes:UP000266906};
RN [1] {ECO:0000313|Proteomes:UP000266906, ECO:0000313|Proteomes:UP000267408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44780 {ECO:0000313|EMBL:ROR34090.1,
RC ECO:0000313|Proteomes:UP000267408}, and DSM 44781
RC {ECO:0000313|EMBL:RPE26900.1, ECO:0000313|Proteomes:UP000266906};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPE26900.1}.
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DR EMBL; RJVJ01000004; ROR34090.1; -; Genomic_DNA.
DR EMBL; RKQG01000005; RPE26900.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4RIF8; -.
DR Proteomes; UP000266906; Unassembled WGS sequence.
DR Proteomes; UP000267408; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR21708:SF26; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
FT DOMAIN 32..162
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 201..310
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 299..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 340 AA; 35171 MW; 238DE31615C9F228 CRC64;
MSGTPAAAPA PEQQPASRQP APEQQPAGLR HAVLGAGGVG LSLAADLARA GQRVVLVMRP
SSLADYRGAV RVRSAGQGDF RVPVPAVARL DEPVDVLWIA VKQPRLAAAL QSVSAAAAPA
LVVPLLNGID HLPLLERDFG DRVVAGAIRI EAHRTAVGEV VRDSLFTQLE LARRNGSRDG
LDPLVAALRT AGIRAVPGRD AQTVLWHKAV LLAPLALATL AVSGPLEQVR AEAEAGTLML
ACARELCAVA TALGVPDLDP DHLIRTLESL PGRTTPSLSR DPAELDAIGG SVLRAAERAG
VPAPATRALL RPRNPAAPNN PNTPKTRTHG QTTKAGSGNA
//
