ID   A0A3N4RJA2_9ACTN        Unreviewed;       636 AA.
AC   A0A3N4RJA2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=NHL repeat-containing protein {ECO:0000313|EMBL:RPE33433.1};
GN   ORFNames=EDD38_1723 {ECO:0000313|EMBL:RPE33433.1};
OS   Kitasatospora cineracea.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Kitasatospora.
OX   NCBI_TaxID=88074 {ECO:0000313|EMBL:RPE33433.1, ECO:0000313|Proteomes:UP000266906};
RN   [1] {ECO:0000313|EMBL:RPE33433.1, ECO:0000313|Proteomes:UP000266906}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44781 {ECO:0000313|EMBL:RPE33433.1,
RC   ECO:0000313|Proteomes:UP000266906};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RPE33433.1}.
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DR   EMBL; RKQG01000001; RPE33433.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N4RJA2; -.
DR   Proteomes; UP000266906; Unassembled WGS sequence.
DR   CDD; cd14951; NHL-2_like; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR045302; NHL2_NHL_rpt_dom.
DR   InterPro; IPR001258; NHL_repeat.
DR   InterPro; IPR012336; Thioredoxin-like_fold.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR46388; NHL REPEAT-CONTAINING PROTEIN 2; 1.
DR   PANTHER; PTHR46388:SF2; NHL REPEAT-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF01436; NHL; 1.
DR   Pfam; PF13905; Thioredoxin_8; 1.
DR   SUPFAM; SSF101898; NHL repeat; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS51125; NHL; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          33..179
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   REPEAT          418..463
FT                   /note="NHL"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   636 AA;  67784 MW;  EB94CAF603EB1820 CRC64;
     MPAPETAPPA RPALTARPAG SRRAMRFTWG MTSRARVRAP ELVGKGGWLN TGGKDLSLVD
     FRGKIVIADF WTFCCINCLH VLDELRELEE KHRDTVVIVG VHSPKFVHEA DHRAVVDAVA
     RYEVHHPVLD DPELVTWKQY AVRAWPTLVV IDPEGYVVAQ HAGEGHAHAI AKLVEELEAE
     HAAKGTLRRG DGPYVAPEPE AGDLRFPGKA VRLPDGHYLV ADSGHHALVE LDADGETVLR
     RIGDGVRGLV DGAAPRFSEP QGLALVPEGL GLGYDVVVAD TVNHALRGVR LADGSVTTLA
     GTGKQWWQGS PTSGAAREVD LSSPWDVAFF DGRVWIAMAG VHQLWSFDPA AGTVAVAAGT
     TNEGLVDGPA DEAWFAQPSG LAVSADGERM WVADSETSAL RWVSRGTHEV RTAVGTGLFD
     FGHRDGAAGQ ALLQHPLGVT VLPDGSVAVS DTYNHALRRY DPASGEVSTL ATDLREPSGA
     VVVDGDIVVV ESARHRLTRL RLPEEAVRVE AVAHRTRRAA TEVAPGALRL DVVFSAPTGQ
     KLDERYGPST RLLVSATPPE LLVSGAGADS ALSRELVLSD EVAEGVLHVS AMAASCDDDP
     EIEYPACHVH QQDWGVPVRL VAGGAGRLPL VLAGME
//