ID A0A3N4RRZ0_9ACTN Unreviewed; 575 AA.
AC A0A3N4RRZ0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:RPE36168.1};
GN ORFNames=EDD38_4536 {ECO:0000313|EMBL:RPE36168.1};
OS Kitasatospora cineracea.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=88074 {ECO:0000313|EMBL:RPE36168.1, ECO:0000313|Proteomes:UP000266906};
RN [1] {ECO:0000313|EMBL:RPE36168.1, ECO:0000313|Proteomes:UP000266906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44781 {ECO:0000313|EMBL:RPE36168.1,
RC ECO:0000313|Proteomes:UP000266906};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPE36168.1}.
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DR EMBL; RKQG01000001; RPE36168.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4RRZ0; -.
DR Proteomes; UP000266906; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 2..308
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 353..465
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 484..542
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 137
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 213
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 575 AA; 63515 MW; 657FB7DAF24C7F86 CRC64;
MRVLSGAMHY FRTLPQQWPD RLRKLRAMGL DTVETYVPWN LHEPRPGEFD FTGPLDLERF
LDEAAAAGLW AIVRPGPYIC AEFDNGGLPS WLPGPLRCAD PGFLEPMDRY FDQVVPLIAR
HQATRGGRVT MVQVENEYGS YGNDRTYLQH IADGLRDRGI EVPLFTSDGA GDLFLTGGTL
PGVQATVNFG GRAGEQFAAF TKHRPQDPLF CMEYWNGWFD HWRDQHIVRD PADAAAGLDD
ILSRGASVNI YMAVGGTNFG FTAGANADGP YVDGAYQPTV TSYDYDAPIA EDGTLTPKYH
AYREVLKNHT ALPPLPEEDH PTLPAARLEA VDRLALLDCL DVLSTGTVRS AVPPTFEELG
ISHGLAVHTT RVSGPRDEPG MPLRTPGLRD RAHVFLDRQP LGVLERDTAE ELPELRVPAD
GADLTLVVES MGRVNYGPLT GERKGITRGV LHERQFLFGW ETEPVPLDDI SGLPWGRPSA
LPGPAFLRTH LEVAEPADGY LALSGWGKGH VWINGFHLGR YWQTGPQETL YLPWPLLHRG
SNEITVLELD RVPARPLITI EPAPSLGTPR ESHSK
//
