ID A0A3N4S0Z5_9ACTN Unreviewed; 328 AA.
AC A0A3N4S0Z5; A0A8G1UHE4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=deoxyribose-phosphate aldolase {ECO:0000256|ARBA:ARBA00012515};
DE EC=4.1.2.4 {ECO:0000256|ARBA:ARBA00012515};
DE AltName: Full=2-deoxy-D-ribose 5-phosphate aldolase {ECO:0000256|ARBA:ARBA00032755};
DE AltName: Full=Phosphodeoxyriboaldolase {ECO:0000256|ARBA:ARBA00031814};
GN ORFNames=EDD38_2712 {ECO:0000313|EMBL:RPE34397.1}, EDD39_2223
GN {ECO:0000313|EMBL:ROR44050.1};
OS Kitasatospora cineracea.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=88074 {ECO:0000313|EMBL:RPE34397.1, ECO:0000313|Proteomes:UP000266906};
RN [1] {ECO:0000313|Proteomes:UP000266906, ECO:0000313|Proteomes:UP000267408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44780 {ECO:0000313|EMBL:ROR44050.1,
RC ECO:0000313|Proteomes:UP000267408}, and DSM 44781
RC {ECO:0000313|EMBL:RPE34397.1, ECO:0000313|Proteomes:UP000266906};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde
CC 3-phosphate; Xref=Rhea:RHEA:12821, ChEBI:CHEBI:15343,
CC ChEBI:CHEBI:59776, ChEBI:CHEBI:62877; EC=4.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000764};
CC -!- PATHWAY: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate
CC degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-
CC deoxy-alpha-D-ribose 1-phosphate: step 2/2.
CC {ECO:0000256|ARBA:ARBA00004816}.
CC -!- SIMILARITY: Belongs to the DeoC/FbaB aldolase family. DeoC type 2
CC subfamily. {ECO:0000256|ARBA:ARBA00009473}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPE34397.1}.
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DR EMBL; RJVJ01000001; ROR44050.1; -; Genomic_DNA.
DR EMBL; RKQG01000001; RPE34397.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4S0Z5; -.
DR Proteomes; UP000266906; Unassembled WGS sequence.
DR Proteomes; UP000267408; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004139; F:deoxyribose-phosphate aldolase activity; IEA:UniProtKB-EC.
DR GO; GO:0009264; P:deoxyribonucleotide catabolic process; IEA:InterPro.
DR CDD; cd00959; DeoC; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR011343; DeoC.
DR InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR NCBIfam; TIGR00126; deoC; 1.
DR PANTHER; PTHR10889; DEOXYRIBOSE-PHOSPHATE ALDOLASE; 1.
DR PANTHER; PTHR10889:SF3; DEOXYRIBOSE-PHOSPHATE ALDOLASE; 1.
DR Pfam; PF01791; DeoC; 1.
DR SMART; SM01133; DeoC; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
SQ SEQUENCE 328 AA; 34321 MW; E7936453828AA7FB CRC64;
MSTLAANAPG AAGGGLADVA ASEATLRRFL HGLPGVDQVG LESRAATLGT RSIKTTAKAF
AIDLAISMID LTTLEGADTV GKVRSLCAKG LSPDPSDRST PRVAAICVYP DMVATAKEAL
RGSGVQVASV ATAFPSGRAG LPVKLADTAE AVAAGADEID MVIDRGAFLS GRYLEVFETI
GAVKAACERP DGTSAHLKVI FETGELQTYD NVRRASWLAM IAGADFIKTS TGKVAVNATP
PVTLLMLEAV RDFRAATGVQ IGVKPAGGIR TTKDAMKYLV MVNETLGDDW LSPHWFRFGA
SSLLNDLLMQ RQKLSTGRYS GPDYVTVD
//
