ID A0A3N4YKP1_9MICO Unreviewed; 517 AA.
AC A0A3N4YKP1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=aldehyde dehydrogenase (NAD(+)) {ECO:0000256|ARBA:ARBA00024226};
DE EC=1.2.1.3 {ECO:0000256|ARBA:ARBA00024226};
GN ORFNames=EDD34_1254 {ECO:0000313|EMBL:RPF20657.1};
OS Myceligenerans xiligouense.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Myceligenerans.
OX NCBI_TaxID=253184 {ECO:0000313|EMBL:RPF20657.1, ECO:0000313|Proteomes:UP000280501};
RN [1] {ECO:0000313|EMBL:RPF20657.1, ECO:0000313|Proteomes:UP000280501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15700 {ECO:0000313|EMBL:RPF20657.1,
RC ECO:0000313|Proteomes:UP000280501};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPF20657.1}.
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DR EMBL; RKQZ01000001; RPF20657.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4YKP1; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000280501; Unassembled WGS sequence.
DR GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR044638; ALDH7A1-like.
DR PANTHER; PTHR43521; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43521:SF1; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000280501}.
FT DOMAIN 40..497
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 271
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 517 AA; 53690 MW; 6E4EA2F837556DAD CRC64;
MTATTPAQSI SPLSAELRTA ALAALERLGA SVPEAADDAG LPVRSPLSGE RIVTVRRDGA
EETRAAVAQA ADAFTAWRSV PAPARGHVIK RFGELLAEHK ADLAELVTIE AGKITSEALG
EVQEMIDICD FALGLSRSIG GRTVPSERPG HRLMETWHPL GVVGVISAFN FPVAVWSWNT
AVALVCGDTV VWKPSEKTLL SAIGSAALLD RALVEAGYPS EVSRLVLGEL EAGEALVADE
RVALLSATGS ERMGAAVAPV VAGRMGRYLL ELGGNNAAVV TPSADLDLTT RGVVFSAAGT
AGQRCTTLRR LIVHSSIVDD VVARLVRAYE GLPIGDPRAD GTLVGPLVDA GSAERMAQAL
AEARADGGEV LVGGGQVTVD DAPGATYVAP AIVRMPAQTA VVRRETFAPV LYVMTYETLD
EAIALHNGVP QGLSSSIFTL DAREAERFLS EAGSDCGIAN VNIGTSGAEI GGAFGGEKST
GGGRESGSDA WKQYMRRATN TINYSDELPL AQGVNFG
//
