ID A0A3N4YLE2_9MICO Unreviewed; 275 AA.
AC A0A3N4YLE2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Glyoxylase-like metal-dependent hydrolase (Beta-lactamase superfamily II) {ECO:0000313|EMBL:RPF20927.1};
GN ORFNames=EDD34_1534 {ECO:0000313|EMBL:RPF20927.1};
OS Myceligenerans xiligouense.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Myceligenerans.
OX NCBI_TaxID=253184 {ECO:0000313|EMBL:RPF20927.1, ECO:0000313|Proteomes:UP000280501};
RN [1] {ECO:0000313|EMBL:RPF20927.1, ECO:0000313|Proteomes:UP000280501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15700 {ECO:0000313|EMBL:RPF20927.1,
RC ECO:0000313|Proteomes:UP000280501};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPF20927.1}.
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DR EMBL; RKQZ01000001; RPF20927.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N4YLE2; -.
DR OrthoDB; 2971563at2; -.
DR Proteomes; UP000280501; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd06262; metallo-hydrolase-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR46233; HYDROXYACYLGLUTATHIONE HYDROLASE GLOC; 1.
DR PANTHER; PTHR46233:SF3; HYDROXYACYLGLUTATHIONE HYDROLASE GLOC; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:RPF20927.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000280501}.
FT DOMAIN 16..258
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT REGION 168..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 275 AA; 27837 MW; B42BA03EA43E272E CRC64;
MSVAAQVDVV VAPVFGTNCC VVAAPGSGVR DCVVVDAGAG VADGVARVVE ERRLRPRAVL
ATHGHADHTW DAAELCERYD VPMWMHAADV YRLDDPFGTL VSGAGAAAVS SALGRELAAL
GFAPEAYRAP KPVEGFETRG GSADLTFGAV TLRAVHAPGH TQGSTLYLLD PPGSDGGAAG
RGGTGEDART GGRTTTGAEA DAATPDSAPS GIVLTGDVLF AGSIGRTDLP GGDDATMRAT
LSDVVARLDP GLAVVPGHGP TTTVERELAT NPYLR
//
