ID A0A3N4ZLX8_9MICO Unreviewed; 1507 AA.
AC A0A3N4ZLX8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Putative repeat protein (TIGR01451 family) {ECO:0000313|EMBL:RPF20931.1};
GN ORFNames=EDD34_1538 {ECO:0000313|EMBL:RPF20931.1};
OS Myceligenerans xiligouense.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Myceligenerans.
OX NCBI_TaxID=253184 {ECO:0000313|EMBL:RPF20931.1, ECO:0000313|Proteomes:UP000280501};
RN [1] {ECO:0000313|EMBL:RPF20931.1, ECO:0000313|Proteomes:UP000280501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15700 {ECO:0000313|EMBL:RPF20931.1,
RC ECO:0000313|Proteomes:UP000280501};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPF20931.1}.
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DR EMBL; RKQZ01000001; RPF20931.1; -; Genomic_DNA.
DR OrthoDB; 9813435at2; -.
DR Proteomes; UP000280501; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR Gene3D; 2.60.120.380; -; 1.
DR Gene3D; 2.60.40.740; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR047589; DUF11_rpt.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007280; Peptidase_C_arc/bac.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR NCBIfam; TIGR01451; B_ant_repeat; 1.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF468; SUBTILISIN-LIKE PROTEASE SBT3.18; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF04151; PPC; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000280501};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..1507
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039033024"
FT DOMAIN 143..185
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 213..670
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 456..539
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 871..940
FT /note="Peptidase C-terminal archaeal/bacterial"
FT /evidence="ECO:0000259|Pfam:PF04151"
FT REGION 288..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 222
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 293
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 617
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 1507 AA; 153999 MW; 9CC009415E2C5F8B CRC64;
MSHRSRTPLV IAAVTALAAA LTPAAVAVPT PGPASDKVEP RELIAENLTP AETTPEPGVE
REPTIQKLAL GRGGAERTYL IRLADDAVPT YRGGVAGLDA TAVRPGGTLD TSVSRVREYT
EFLEAEQDDF VTRMERTVAR DVEVPFSYQY AVNGISAVLT PAEAAEVAKD PAVAHIALDK
EHELHTDSGP AWSNADALWS AVEELGLPED YRGEGVVIGT IDTGINPGSP SFAETGDDGY
THTNPLGAGN YLGACDPSNT DQYDPDFPCN GKLIGAYGFI SDADRSALDD DGHGTHTAST
SGGSVVAGAT PTAPEGTDPP TFDVSGVAPH ANVISYRGCC TTAGLTASID QAIADGVDVI
NYSIGSSAPS DLWNDFDSIG FLNARAAGIF VATSNGNDGP GVATTGSPAD APWLTSVGAS
THNRHAFNTL TGLTGSAGDL PDLTGKSLTG PLPATEIVYA GAFGDPECTT TTGHEADYTD
RIVICDRGSN GRVEKSENVA AQGAVGYVLA NDEANGDSVL GDAYAVPGVF LGYDDATTLK
NWLEEGTGHT ATITGTTFTV DDGLGDVMAS FSSRGPNRAV DTIVPSLTAP GVDILAALGD
ADGAYDHVEY GIISGTSMSS PHVAGAGALL TQARPDWTPA QQQSALMTTA RTGVLNHDGT
PATPYAQGSG HMDIGAAVRA GLLFDESPAD YLAADPEQGG DPSTLNLPSF ADTQCLATCS
WERTAEAPPS APAGVTWSAS ADSDPGLALS VDLSQVTVSP GDSTGITVTA DVAGATEGET
LFGRITLTPS DPEVPAVTLP VAVVPAAAVL PGEIDITTRR DAGSQAVTDV RSVAVTDFTG
SVRGLVAADL HEGSLDEDPT NDSPYDDLSQ VEVTTVEVAD GAERLVAQIT QATAPDLDLF
VGTGDTPSAA TQECASTSGS AAEYCEVPDP EAGTWWVLVQ NWGGSDSQPD THTLATAVVP
SEDLGNAGVA GPDGEVPVGE PYDVRVHWDL PDAQEGDLFF GTAVLGSSPD TPGDIGEVPV
RLARVADDVT KTASTDAAAI GDTIGYDLTV EPNVTPEDLT YTVTDTVPEG LSIDPESVTG
GGVVDGQTIT WEVEMPTSVG VAGAYEASTP ATDPQCAAWA GFVDLGAVGV GFSSLDGDSA
AVSAFSNIGP FSHYSDQSPN LTVSDDGLIT VAGGYGGSPW EPQALPAAAA PNGVIAPLWS
DLELSLANDR GVRLATSGGE VAVVQWDDPF PYGADPADLS NSVGTFQAWI YNSVSEDRPE
ITFEYGELGT LPGLATIGVE NLAGTLGTAV VNAGDPSVAV AEGGSICLDY VGPSVEPVTL
SYDVTVDPDA ITGTYTNTAE HVTADPFDAP ATASADVAVT GLAPCDEVIT GRHHERVSVT
EGTTCIDDAT VVGRVTVSDG AGLRVTDSKI VALVRADGAS EMRVCDSRVL GTLTVIRSSG
VTIGDPSANC AGNRVTGLVT VSRSEGPVIG DNRITGPLAC YRNDPAPVNN GAPNTVTGRQ
FGQCRDL
//
