ID A0A3N5ABC1_9MICO Unreviewed; 356 AA.
AC A0A3N5ABC1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:RPF28941.1};
GN ORFNames=EDD32_3492 {ECO:0000313|EMBL:RPF28941.1};
OS Georgenia muralis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Bogoriellaceae;
OC Georgenia.
OX NCBI_TaxID=154117 {ECO:0000313|EMBL:RPF28941.1, ECO:0000313|Proteomes:UP000280726};
RN [1] {ECO:0000313|EMBL:RPF28941.1, ECO:0000313|Proteomes:UP000280726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14418 {ECO:0000313|EMBL:RPF28941.1,
RC ECO:0000313|Proteomes:UP000280726};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPF28941.1}.
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DR EMBL; RKRA01000001; RPF28941.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N5ABC1; -.
DR OrthoDB; 37081at2; -.
DR Proteomes; UP000280726; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000280726};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 22..76
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 36805 MW; D56B2F878BE4F795 CRC64;
MSVEDDPAGD GDAAAPDAPS SLTMEDVAAA AGVSRTSVSR VMLGQKKVSE DTRRRVFAAA
DRLGYVPNVL ASELASRGTS TIGLLLRDAA NPAYGLLFTQ LQEAAHAADL TLVSMTVTAD
NRGQRQVAGL HRLMGMRVGG LIVATGGVTS EQLEPFCSRI PIIRAGRPET TEHIHAVSYD
EVHAGRTLAE HVADAGHRDV AIVVTAEGDS YPEFVRGTTM AATLAGRGVR IIPVPVGAGP
RGGVDEAVAL ATEGRVSAIM CPSDLRQLEV LRSLAAAGVS VPGDVSVTGC DGVLHGADLL
GLTTYRIPVE QLAVRTVARM AELLAARPGA GVVAERLPGV LVPGRTVGPP SSRKEP
//
