ID A0A3N5C0R4_9THEO Unreviewed; 731 AA.
AC A0A3N5C0R4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=HD domain-containing protein {ECO:0000259|PROSITE:PS51831};
GN ORFNames=EDD75_0571 {ECO:0000313|EMBL:RPF49751.1};
OS Thermodesulfitimonas autotrophica.
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermodesulfitimonas.
OX NCBI_TaxID=1894989 {ECO:0000313|EMBL:RPF49751.1, ECO:0000313|Proteomes:UP000282654};
RN [1] {ECO:0000313|EMBL:RPF49751.1, ECO:0000313|Proteomes:UP000282654}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 102936 {ECO:0000313|EMBL:RPF49751.1,
RC ECO:0000313|Proteomes:UP000282654};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPF49751.1}.
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DR EMBL; RKRE01000001; RPF49751.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N5C0R4; -.
DR Proteomes; UP000282654; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000282654};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 495..639
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT REGION 698..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..714
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 731 AA; 78858 MW; 21D7572B91D1F10F CRC64;
MLHRSADMAG VFFASLKQTL QNPRVRRAGA ALFLFLAATL LLSFRFYPER VNLKVGQVAP
RTIKAPRTVV FEDKVRTEEL RREAASRVPR MYDLDPRVVD SIITETGEII KAVARVAGDQ
SADVQAKEAA LREALPFPLA DGVIKALVRT PPAKLDRLGR ELGGIIQQVM ADGVRQEDLV
AAKKAAAERI EFLSAEPAEK ALARAIVQHT LRPNKFYNAA RTEMLQQEAA EAVAPVEIMV
RAGEKIIGEG EVVTPEHLAK LKAVGLYEAR LSVAALVGVA FTVLLLVLGL FYYLYQQHRE
IYRETSYLYL IALVIAGVLL VAKLILAINV RQASGFSAQL GYAVPVATAG MLLAILLNAR
VAAFAVSVTA ILVGMMTGDE LRFMLCGFLT GITGVLSVSR LSRRGDLVRA GLYVGGAAVF
AAVAVGLFSG TPPQLLLPVS LGLGLANGLL SSILTNGALP VIDYLSGITS PVKLLELTNP
GEPLLKRLLM EAPGTYHHSI LVGNLGEAAA EAIGADILTV RAGAYYHDIG KLRRPSFFIE
NQMGQENPHD KLAPTLSTLI VTSHVKDGVE LARTYRLPEK IVEIIEQHHG TSLAGFFYQK
ALEADQKKPP NERDFRYPGP KPQTREAAIV MLADAVEAAV RALGQPAPGQ VEGLVRRIIK
EKLYDGQLDE SALTFRDLEM IAVAFTKVLS GIFHSRLEYP EREGGKEDSG GSDSPKPARK
GPGAGESDVA G
//
