ID A0A3N6ETU3_9ACTN Unreviewed; 265 AA.
AC A0A3N6ETU3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Hydrogenase isoenzymes nickel incorporation protein HypB {ECO:0000313|EMBL:RPK54501.1};
GN Name=hypB {ECO:0000313|EMBL:RPK54501.1};
GN ORFNames=EES43_28425 {ECO:0000313|EMBL:RPK54501.1};
OS Streptomyces sp. ADI96-02.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1522760 {ECO:0000313|EMBL:RPK54501.1, ECO:0000313|Proteomes:UP000273170};
RN [1] {ECO:0000313|EMBL:RPK54501.1, ECO:0000313|Proteomes:UP000273170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ADI96-02 {ECO:0000313|EMBL:RPK54501.1,
RC ECO:0000313|Proteomes:UP000273170};
RA Guerrero-Garzon J.F., Zehl M., Urban E., Schneider O., Ruckert C.,
RA Busche T., Kalinowski J., Zotchev S.B.;
RT "Streptomyces spp. from the marine sponge Antho dichothoma: analyses of
RT secondary metabolite biosynthesis gene clusters and some of their
RT products.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM
CC subfamily. {ECO:0000256|ARBA:ARBA00006211}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPK54501.1}.
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DR EMBL; RPGW01000187; RPK54501.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N6ETU3; -.
DR OrthoDB; 9802035at2; -.
DR Proteomes; UP000273170; Unassembled WGS sequence.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR GO; GO:0051604; P:protein maturation; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR004392; Hyd_mat_HypB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00073; hypB; 1.
DR PANTHER; PTHR30134:SF2; HYDROGENASE MATURATION FACTOR HYPB; 1.
DR PANTHER; PTHR30134; HYDROGENASE PROTEIN ASSEMBLY PROTEIN, NICKEL CHAPERONE; 1.
DR Pfam; PF02492; cobW; 1.
DR PIRSF; PIRSF005624; Ni-bind_GTPase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nickel {ECO:0000256|ARBA:ARBA00022596};
KW Reference proteome {ECO:0000313|Proteomes:UP000273170};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 34..195
FT /note="CobW/HypB/UreG nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02492"
FT REGION 229..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..248
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 265 AA; 28138 MW; 2386C8CD02189931 CRC64;
MCRTVDLHQA VLAKNDTNAV ELRRVLDGRG TVAVNLMSSP GSGKTALLEE LLTRARAAGT
PAAAVTADLA TENDATRLAR SGAPVRQILT DGLCHLEAGM LRHTLEDWLP ERTRLLFVEN
VGNLVCPASY DLGETLRIVL ASVTEGEDKP VKYPAAFGLA QLVVVTKTDL AEAVEFRRDT
FLGGVQRVNP GVPVIETSAR TGEGVDALLA HVLRAADGRE THTPVLARQH GEHPHHHGTG
EDAAAPHPSA HRHPAAAPAP ARPGR
//
