ID A0A3N6F514_9ACTN Unreviewed; 348 AA.
AC A0A3N6F514;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=(2E,6E)-farnesyl diphosphate synthase {ECO:0000313|EMBL:RPK58221.1};
DE EC=2.5.1.10 {ECO:0000313|EMBL:RPK58221.1};
GN ORFNames=EES43_20100 {ECO:0000313|EMBL:RPK58221.1};
OS Streptomyces sp. ADI96-02.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1522760 {ECO:0000313|EMBL:RPK58221.1, ECO:0000313|Proteomes:UP000273170};
RN [1] {ECO:0000313|EMBL:RPK58221.1, ECO:0000313|Proteomes:UP000273170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ADI96-02 {ECO:0000313|EMBL:RPK58221.1,
RC ECO:0000313|Proteomes:UP000273170};
RA Guerrero-Garzon J.F., Zehl M., Urban E., Schneider O., Ruckert C.,
RA Busche T., Kalinowski J., Zotchev S.B.;
RT "Streptomyces spp. from the marine sponge Antho dichothoma: analyses of
RT secondary metabolite biosynthesis gene clusters and some of their
RT products.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPK58221.1}.
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DR EMBL; RPGW01000132; RPK58221.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N6F514; -.
DR OrthoDB; 4497239at2; -.
DR Proteomes; UP000273170; Unassembled WGS sequence.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR NCBIfam; NF041169; f2_encap_cargo4; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000273170};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:RPK58221.1}.
SQ SEQUENCE 348 AA; 35805 MW; 0C1C8B54810C423C CRC64;
MTSTDAAATE GHEAAALLEH TRAVVDPPLR AAVESLPAGI RRVAMYHFGW ENADGTPASG
QAGKAIRPAL VLAAARALGG DPEQAVRAAV AVELAHNFTL LHDDVIDEDT TRRHRPTAWA
VFGIPDAVIT GDALLALAQQ LLAEDPHPAA ARAAARLSAC VIELCAGQQT DCAFEERGPD
EVTLDACLAM ATAKTGALLG CACSLGALYA GAEDRVVGAM DGFGREAGLS FQLIDDLIGI
WGDPARTGKP VGADLSAHKK SLPVVAALTS GTPAAAELAA LYRGELSAPA EVALAADCVD
RAGGRDWAQA AAADRMARAV HHLSRAVPDP SAADDLLALA EFVTRRTS
//
