ID A0A3N6FVY4_9ACTN Unreviewed; 229 AA.
AC A0A3N6FVY4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=Putative metallo-hydrolase {ECO:0000313|EMBL:RPK67320.1};
DE EC=3.-.-.- {ECO:0000313|EMBL:RPK67320.1};
GN ORFNames=EES43_03790 {ECO:0000313|EMBL:RPK67320.1};
OS Streptomyces sp. ADI96-02.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1522760 {ECO:0000313|EMBL:RPK67320.1, ECO:0000313|Proteomes:UP000273170};
RN [1] {ECO:0000313|EMBL:RPK67320.1, ECO:0000313|Proteomes:UP000273170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ADI96-02 {ECO:0000313|EMBL:RPK67320.1,
RC ECO:0000313|Proteomes:UP000273170};
RA Guerrero-Garzon J.F., Zehl M., Urban E., Schneider O., Ruckert C.,
RA Busche T., Kalinowski J., Zotchev S.B.;
RT "Streptomyces spp. from the marine sponge Antho dichothoma: analyses of
RT secondary metabolite biosynthesis gene clusters and some of their
RT products.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPK67320.1}.
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DR EMBL; RPGW01000018; RPK67320.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N6FVY4; -.
DR OrthoDB; 9802991at2; -.
DR Proteomes; UP000273170; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd06262; metallo-hydrolase-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR46233; HYDROXYACYLGLUTATHIONE HYDROLASE GLOC; 1.
DR PANTHER; PTHR46233:SF3; HYDROXYACYLGLUTATHIONE HYDROLASE GLOC; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:RPK67320.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000273170}.
FT DOMAIN 12..202
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT REGION 201..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 229 AA; 23922 MW; 96DA4D1DFE4467ED CRC64;
MLIAGFPAGA WGTNCYLVAP AAGEECVIID PGHQAAQGVE EALKKHRLKP VAVVLTHGHI
DHVASVVPVC GAHDVPAWIH PEDRYMMSDP EKALGRSIGM PLMGELTVGE PDDVKELTDG
SRLALAGLEF GVSHAPGHTK GSVTFGMPEA ADVPPVLFSG DLLFAGSVGR TDLPGGDHAE
LIESLARVCL PLDDSTVVLS GHGPQTTIGR ERASNPFLNG LDAPPRRGM
//
