ID A0A3N6GJ71_9ACTN Unreviewed; 278 AA.
AC A0A3N6GJ71;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=D-aminopeptidase {ECO:0000313|EMBL:RPK84034.1};
DE EC=3.4.11.- {ECO:0000313|EMBL:RPK84034.1};
GN Name=dppA3 {ECO:0000313|EMBL:RPK84034.1};
GN ORFNames=EES45_05210 {ECO:0000313|EMBL:RPK84034.1};
OS Streptomyces sp. ADI97-07.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1522762 {ECO:0000313|EMBL:RPK84034.1, ECO:0000313|Proteomes:UP000281409};
RN [1] {ECO:0000313|EMBL:RPK84034.1, ECO:0000313|Proteomes:UP000281409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ADI97-07 {ECO:0000313|EMBL:RPK84034.1,
RC ECO:0000313|Proteomes:UP000281409};
RA Guerrero-Garzon J.F., Zehl M., Urban E., Schneider O., Ruckert C.,
RA Busche T., Kalinowski J., Zotchev S.B.;
RT "Streptomyces spp. from the marine sponge Antho dichothoma: analyses of
RT secondary metabolite biosynthesis gene clusters and some of their
RT products.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPK84034.1}.
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DR EMBL; RPGY01000023; RPK84034.1; -; Genomic_DNA.
DR RefSeq; WP_056792227.1; NZ_ML123098.1.
DR AlphaFoldDB; A0A3N6GJ71; -.
DR Proteomes; UP000281409; Unassembled WGS sequence.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08663; DAP_dppA_1; 1.
DR Gene3D; 3.30.1360.130; Dipeptide transport protein; 1.
DR Gene3D; 3.40.50.10780; Dipeptide transport protein; 1.
DR InterPro; IPR027476; DppA_N.
DR InterPro; IPR007035; Peptidase_M55.
DR InterPro; IPR036177; Peptidase_M55_sf.
DR Pfam; PF04951; Peptidase_M55; 1.
DR PIRSF; PIRSF015853; Pep_DppA; 1.
DR SUPFAM; SSF63992; Dipeptide transport protein; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000313|EMBL:RPK84034.1};
KW Hydrolase {ECO:0000313|EMBL:RPK84034.1};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR015853-2};
KW Protease {ECO:0000313|EMBL:RPK84034.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000281409};
KW Zinc {ECO:0000256|PIRSR:PIRSR015853-2}.
FT ACT_SITE 116
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-1"
FT BINDING 8
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 8
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 10
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 60
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 105
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 135
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
SQ SEQUENCE 278 AA; 29494 MW; 7DA480B7EA81E6F0 CRC64;
MKILVSADME GATGVTWPAD VLPGTPQWER CRAMFTSDVN AAALGFYDGG ADEVLVNEAH
WSMRNLLLEQ LDDRVQMLTG RHKSLSMVEG IQHGDVDAVA FIGYHTGAGA EGVLAHTYLA
NSITGVWLNG VRASEGLLNA HVAAEYGVPV ILVTGDDLTC KDAELYAPAA RMVAVKDHVS
RYAAVCRTPA RTAADIRAAA SEATALAVRH APVTTGDGYT VQLEFDAEHL AAAATVVPGV
ARDGERRVAY TSGTMYEGIR TFKAVTTIVS SAVEEQYG
//
