ID A0A3N6GRK2_9ACTN Unreviewed; 201 AA.
AC A0A3N6GRK2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Oligoribonuclease {ECO:0000256|HAMAP-Rule:MF_00045};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00045};
GN Name=orn {ECO:0000256|HAMAP-Rule:MF_00045,
GN ECO:0000313|EMBL:RPK76961.1};
GN ORFNames=EES45_22265 {ECO:0000313|EMBL:RPK76961.1};
OS Streptomyces sp. ADI97-07.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1522762 {ECO:0000313|EMBL:RPK76961.1, ECO:0000313|Proteomes:UP000281409};
RN [1] {ECO:0000313|EMBL:RPK76961.1, ECO:0000313|Proteomes:UP000281409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ADI97-07 {ECO:0000313|EMBL:RPK76961.1,
RC ECO:0000313|Proteomes:UP000281409};
RA Guerrero-Garzon J.F., Zehl M., Urban E., Schneider O., Ruckert C.,
RA Busche T., Kalinowski J., Zotchev S.B.;
RT "Streptomyces spp. from the marine sponge Antho dichothoma: analyses of
RT secondary metabolite biosynthesis gene clusters and some of their
RT products.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: 3'-to-5' exoribonuclease specific for small
CC oligoribonucleotides. {ECO:0000256|HAMAP-Rule:MF_00045}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00045}.
CC -!- SIMILARITY: Belongs to the oligoribonuclease family.
CC {ECO:0000256|ARBA:ARBA00009921, ECO:0000256|HAMAP-Rule:MF_00045}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RPK76961.1}.
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DR EMBL; RPGY01000109; RPK76961.1; -; Genomic_DNA.
DR RefSeq; WP_056798771.1; NZ_ML123099.1.
DR AlphaFoldDB; A0A3N6GRK2; -.
DR Proteomes; UP000281409; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd06135; Orn; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR HAMAP; MF_00045; Oligoribonuclease; 1.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR022894; Oligoribonuclease.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR11046; OLIGORIBONUCLEASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11046:SF0; OLIGORIBONUCLEASE, MITOCHONDRIAL; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00045};
KW Exonuclease {ECO:0000256|HAMAP-Rule:MF_00045};
KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_00045, ECO:0000313|EMBL:RPK76961.1};
KW Nuclease {ECO:0000256|HAMAP-Rule:MF_00045};
KW Reference proteome {ECO:0000313|Proteomes:UP000281409}.
FT DOMAIN 4..178
FT /note="Exonuclease"
FT /evidence="ECO:0000259|SMART:SM00479"
FT REGION 182..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 126
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00045"
SQ SEQUENCE 201 AA; 22192 MW; 931B5E407653317C CRC64;
MNDRMVWIDC EMTGLSLTDD ALIEVAALVT DSELNVLGEG VDIVIRPPDA ALETMPEVVR
QMHTASGLLD ELAGGTTLAD AEERVLAYVR EHVKEPGKAP LCGNSVGTDR GFLSRDMPSL
EGYLHYRIVD VSSVKELSRR WYPRAYFNSP DKNGNHRALA DIRDSITELR YYRDAVFVPQ
PGPDSARAKE IAARHAKPAG Q
//
