ID   A0A3N6HCP8_9ACTN        Unreviewed;       356 AA.
AC   A0A3N6HCP8;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=(2E,6E)-farnesyl diphosphate synthase {ECO:0000313|EMBL:RPK84381.1};
DE            EC=2.5.1.10 {ECO:0000313|EMBL:RPK84381.1};
GN   ORFNames=EES45_03815 {ECO:0000313|EMBL:RPK84381.1};
OS   Streptomyces sp. ADI97-07.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1522762 {ECO:0000313|EMBL:RPK84381.1, ECO:0000313|Proteomes:UP000281409};
RN   [1] {ECO:0000313|EMBL:RPK84381.1, ECO:0000313|Proteomes:UP000281409}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ADI97-07 {ECO:0000313|EMBL:RPK84381.1,
RC   ECO:0000313|Proteomes:UP000281409};
RA   Guerrero-Garzon J.F., Zehl M., Urban E., Schneider O., Ruckert C.,
RA   Busche T., Kalinowski J., Zotchev S.B.;
RT   "Streptomyces spp. from the marine sponge Antho dichothoma: analyses of
RT   secondary metabolite biosynthesis gene clusters and some of their
RT   products.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC       {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RPK84381.1}.
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DR   EMBL; RPGY01000021; RPK84381.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N6HCP8; -.
DR   Proteomes; UP000281409; Unassembled WGS sequence.
DR   GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR   CDD; cd00685; Trans_IPPS_HT; 1.
DR   Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR   InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR   InterPro; IPR000092; Polyprenyl_synt.
DR   InterPro; IPR033749; Polyprenyl_synt_CS.
DR   PANTHER; PTHR12001:SF71; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR   PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR   Pfam; PF00348; polyprenyl_synt; 1.
DR   SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR   SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR   SUPFAM; SSF48576; Terpenoid synthases; 1.
DR   PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
PE   3: Inferred from homology;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Reference proteome {ECO:0000313|Proteomes:UP000281409};
KW   Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:RPK84381.1}.
SQ   SEQUENCE   356 AA;  37805 MW;  904382DAE2490C4C CRC64;
     MTPANPAYDT VADTTDVTAL LERGRALSTP VLRAAVDRLA PPMDTVAAYH FGWIDAQGRP
     ADGDGGKAVR PALALLSAEA AGAPPEAGIP GAVAVELVHN FSLLHDDLMD GDEQRRHRDT
     VWKVHGPAQA ILVGDALFAL ANEILLELGT VEAGRAARRL TTATRKLIDG QAQDISYEHR
     ERVTVEECLE MEGNKTGALL ACAVSIGAVL GGADDRTADT LEAYGYHLGL AFQAVDDLLG
     IWGDPESTGK QTWSDLRQRK KSLPVVAALA AGGPASAQLG ELLAADAKSN DFDSFSEEEF
     AARAALIEEA GGREWTAQEA RRQHAVAIEA LHGVDMPEQV RAQLTALADF VVVRKR
//