ID   A0A3N6HQL1_9ACTN        Unreviewed;       514 AA.
AC   A0A3N6HQL1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=DUF445 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=EES43_09950 {ECO:0000313|EMBL:RPK64355.1};
OS   Streptomyces sp. ADI96-02.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1522760 {ECO:0000313|EMBL:RPK64355.1, ECO:0000313|Proteomes:UP000273170};
RN   [1] {ECO:0000313|EMBL:RPK64355.1, ECO:0000313|Proteomes:UP000273170}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ADI96-02 {ECO:0000313|EMBL:RPK64355.1,
RC   ECO:0000313|Proteomes:UP000273170};
RA   Guerrero-Garzon J.F., Zehl M., Urban E., Schneider O., Ruckert C.,
RA   Busche T., Kalinowski J., Zotchev S.B.;
RT   "Streptomyces spp. from the marine sponge Antho dichothoma: analyses of
RT   secondary metabolite biosynthesis gene clusters and some of their
RT   products.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RPK64355.1}.
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DR   EMBL; RPGW01000044; RPK64355.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N6HQL1; -.
DR   OrthoDB; 9769590at2; -.
DR   Proteomes; UP000273170; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007383; DUF445.
DR   PANTHER; PTHR38442; INNER MEMBRANE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR38442:SF1; INNER MEMBRANE PROTEIN-RELATED; 1.
DR   Pfam; PF04286; DUF445; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000273170};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        114..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   514 AA;  54295 MW;  A0EAF4F60D006B62 CRC64;
     MDETGSGEQD AVRKPGQDPE GTGTETGPAG RDGGDAVAAG ARGATTGKDI GADGPSANGE
     DAPGAGSRSA GPRPEGPQPT GPRSAGSRSA GPLASFAYTA ADEEKQRGVR RMKLTATGLL
     LLVAVVYVLA TWAKNSGVAG WPGYVAAAAE AGMVGALADW FAVTALFRRP LGLPIPHTAI
     IPTKKDQLGQ SLGSFVGENF LSGDVIRDRI HALGVGRRVG AWLAEPEHAE RVTAELATAL
     RGALTVLRDS DVQAVVGEAI TRRADAVEVG PGLGKMLERV VEDGGHRRVV DLVCVRAHDW
     LVEHGESVMD AVQGGAPGWT PRFVDKRVGE RVYKELLRFV TEMRDMPGHP ARASIDTFLT
     DFAADLQSDA DTRVRVERLK SEILGRGEVQ DVIASAWSSV RTMILSAAED ERSELRLRAR
     ASLMSLGARL ASDERLQSKL DGWLEDAAVY VVTTYRAEIT SLISDTVASW DADQTSKKIE
     AHIGRDLQFI RINGTVVGAL AGLAIYSVSR ALGG
//