ID   A0A3N6I7N2_9ACTN        Unreviewed;       404 AA.
AC   A0A3N6I7N2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN   ORFNames=EES45_27960 {ECO:0000313|EMBL:RPK74289.1};
OS   Streptomyces sp. ADI97-07.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1522762 {ECO:0000313|EMBL:RPK74289.1, ECO:0000313|Proteomes:UP000281409};
RN   [1] {ECO:0000313|EMBL:RPK74289.1, ECO:0000313|Proteomes:UP000281409}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ADI97-07 {ECO:0000313|EMBL:RPK74289.1,
RC   ECO:0000313|Proteomes:UP000281409};
RA   Guerrero-Garzon J.F., Zehl M., Urban E., Schneider O., Ruckert C.,
RA   Busche T., Kalinowski J., Zotchev S.B.;
RT   "Streptomyces spp. from the marine sponge Antho dichothoma: analyses of
RT   secondary metabolite biosynthesis gene clusters and some of their
RT   products.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RPK74289.1}.
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DR   EMBL; RPGY01000140; RPK74289.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N6I7N2; -.
DR   Proteomes; UP000281409; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR026367; FxsC_C.
DR   InterPro; IPR047603; FxsC_N.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   NCBIfam; TIGR04276; FxsC_Cterm; 1.
DR   NCBIfam; NF040588; FxsC_Nterm; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000281409}.
FT   DOMAIN          1..140
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   404 AA;  45375 MW;  0CDFE9B47307FE4E CRC64;
     MWVERLFQDL CGHVMAMTDL PAGASAGFMD REIRSGEGWS ERLGSVLATC RVFVPLFSPR
     YFASEMCGKE WHAFEQRAIH HRARSNQSAE AIVPALWVPV PPNQLPGSAE RLQFNHRDFG
     ERYVSDGLYG LIKLRLFAQE YERAVYELAK RIVSVADTVQ IDTGRPVDYR LAPSAFGSPS
     SGVGAPRPMQ ITVAAPTRHD LPEGRIADYY GDHPQDWNPY HPAAARPLAY VAEELVRSLN
     YQAVITSFDE ESGQQEGKQA PSTPEILLVD RWALQDEDRR RRLAAFDAEN RPWVTMVVPW
     CRDDHQSRAA EAELTEKLEQ TMPTKMRQGR AFCRVAAKGV PTMEAFGQVL PQVVEVAAQQ
     YLRHATVYPP AGGRHSERTR LMGPMGSTQF IPDMHDLATD AEDV
//