ID   A0A3N6LK81_9EURY        Unreviewed;       404 AA.
AC   A0A3N6LK81;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=ORC1-type DNA replication protein {ECO:0000256|HAMAP-Rule:MF_01407};
GN   ORFNames=EA462_16725 {ECO:0000313|EMBL:RQG86778.1};
OS   Natrarchaeobius halalkaliphilus.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Natrarchaeobius.
OX   NCBI_TaxID=1679091 {ECO:0000313|EMBL:RQG86778.1, ECO:0000313|Proteomes:UP000273828};
RN   [1] {ECO:0000313|EMBL:RQG86778.1, ECO:0000313|Proteomes:UP000273828}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AArcht-Sl {ECO:0000313|EMBL:RQG86778.1,
RC   ECO:0000313|Proteomes:UP000273828};
RA   Sorokin D.Y., Elcheninov A.G., Kostrikina N.A., Bale N.J.,
RA   Sinninghe Damste J.S., Khijniak T.V., Kublanov I.V., Toshchakov S.V.;
RT   "Natrarchaeobius chitinivorans gen. nov., sp. nov., and Natrarchaeobius
RT   haloalkaliphilus sp. nov., alkaliphilic, chitin-utilizing haloarchaea from
RT   hypersaline alkaline lakes.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000256|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000256|HAMAP-
CC       Rule:MF_01407}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RQG86778.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; REFY01000007; RQG86778.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3N6LK81; -.
DR   OrthoDB; 195574at2157; -.
DR   Proteomes; UP000273828; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd00009; AAA; 1.
DR   CDD; cd08768; Cdc6_C; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR   PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR   PANTHER; PTHR10763:SF22; ORC1-TYPE DNA REPLICATION PROTEIN 3; 1.
DR   Pfam; PF13401; AAA_22; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW   Rule:MF_01407};
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705, ECO:0000256|HAMAP-
KW   Rule:MF_01407};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW   Rule:MF_01407}; Reference proteome {ECO:0000313|Proteomes:UP000273828}.
FT   DOMAIN          54..215
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          313..399
FT                   /note="Cdc6 C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01074"
FT   BINDING         66..70
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT   BINDING         214
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT   BINDING         226
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   404 AA;  45076 MW;  82D55DD58F468E46 CRC64;
     MSDSDDLFIR TDPIFVNKEL LEISHLPEEG RIVGRDEEIG QLANAVNPAI FGQSPSNVLI
     YGKTGTGKSL CAKYVSRRLV STAEEEGVEA VFAYVDCAQD TTETQAAQTI ASSVNTDDTE
     IYIPDKGIST ATYYKRLWRI LDKEYDVALI ILDEIDKLED DAILMQLSRA GEAGKVTECK
     IGVMGISNKI KYKDRMDERV KSSLCEREFV FPPYNASQLN QIMTARSDAF REAVLEDGVI
     PRAAALAARE HGDARKAIDI LRYAGEIAQA NGADTVREDF VVQARERAEV DRFRELIRGS
     TPHSRYALQA LTVLSLEHCA DDLSHENDGF RTTRVYDVYE QICRQEGTDA LSLRRVRDLL
     KEHAFLDVIE QSRHSGGSAE GSYTEHTLLE NPKVVKDVLA DTVD
//